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Polydopamine/dialdehyde starch/chitosan composite coating for in-tube solid-phase microextraction and in-situ derivation to analysis of two liver cancer biomarkers in human blood

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成果类型:
期刊论文、会议论文
作者:
Wu, Shiju;Cai, Cuicui;Cheng, Jing*;Cheng, Min;Zhou, Hongbin;...
通讯作者:
Cheng, Jing
作者机构:
[Wu, Shiju; Zhou, Hongbin; Cheng, Jing; Deng, Jiali; Cai, Cuicui] Cent China Normal Univ, Inst Publ Hlth & Mol Med Anal, Key Lab Pesticide & Chem Biol, Minist Educ,Coll Chem, Wuhan 430079, Peoples R China.
[Cheng, Min] Hua Zhong Univ Sci & Technol, Sch Mech Sci & Engn, Wuhan 430074, Peoples R China.
通讯机构:
[Cheng, Jing] C
Cent China Normal Univ, Inst Publ Hlth & Mol Med Anal, Key Lab Pesticide & Chem Biol, Minist Educ,Coll Chem, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Polydopamine/dialdehyde starch/chitosan composite;HPLC;Polytetrafluoroethlyene tube;Solid-phase microextraction;Hexanal and 2-butanone
期刊:
Analytica Chimica Acta
ISSN:
0003-2670
年:
2016
卷:
935
页码:
113-120
会议名称:
17th International Symposium on Advances in Extraction Technologies
会议时间:
NOV 07-17, 2015
会议地点:
Sun Yat Sen Univ, Guangzhou, PEOPLES R CHINA
会议主办单位:
Sun Yat Sen Univ
出版地:
PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
出版者:
ELSEVIER SCIENCE BV
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
In order to highly enrich two liver cancer biomarkers (hexanal and 2-butanone) in human blood, in this study, natural nontoxic polydopamine/dialdehyde starch/chitosan (PD/DAS/CHI) coating material was synthesized and immobilized on the inner wall of polytetrafluoro-ethlyene (PTFE) tube. It was used to develop the method based on in-tube solid-phase microextraction (IT-SPME) with in-situ derivatization (ISD) coupled to high performance liquid chromatography for the determination of the above mentioned two liver cancer biomarkers in human blood. The simple, rapid and sensitive IT-SPME-ISD method...

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