Noise pollution is recognized as a serious human health problem in modern society. The aim of the present study was to explore the effects of moderate-intensity white noise exposure on learning and memory of mice, and the underlying mechanisms. The learning and memory ability of mice were evaluated by water maze and step-down inhibitory avoidance experiments respectively, following 1, 3, and 6 weeks noise exposure (80 dB SPL, 2 h/day). To explore potential mechanisms, we determined levels of oxidative stress in the inferior colliculus (IC), auditory cortex (AC), and hippocampus (the structures...
