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Synthesis and Biological Activity of Ethyl 4-Alkyl-2-(2-(substituted phenoxy)acetamido)thiazole-5-carboxylate

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成果类型:
期刊论文
作者:
Mo, Wenyan;Shi, Yanxia;He, Junbo;Li, Baoju*;Peng, Hao;...
通讯作者:
He, Hongwu;Li, Baoju
作者机构:
[He, Hongwu; Peng, Hao; He, Junbo; Mo, Wenyan] Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
[He, Hongwu; Peng, Hao; He, Junbo; Mo, Wenyan] Cent China Normal Univ, Coll Chem, Wuhan 430079, Peoples R China.
[Shi, Yanxia; Li, Baoju] Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100081, Peoples R China.
通讯机构:
[He, Hongwu; Li, Baoju] C
Cent China Normal Univ, Key Lab Pesticide & Chem Biol, Minist Educ, Wuhan 430079, Peoples R China.
Cent China Normal Univ, Coll Chem, Wuhan 430079, Peoples R China.
Chinese Acad Agr Sci, Inst Vegetables & Flowers, Beijing 100081, Peoples R China.
语种:
英文
期刊:
Journal of Heterocyclic Chemistry
ISSN:
0022-152X
年:
2016
卷:
53
期:
1
页码:
183-187
基金类别:
National Basic Research Program of ChinaNational Basic Research Program of China [2010CB126100]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [20772042, 21172090]; National Science and Technology support program [2011BAE06B03]; PCSIRTProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT0953]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
(Chemical Equation Presented) A series of novel ethyl 4-(methyl or trifluoromethyl)-2-(2-(substituted phenoxy)acetamido)thiazole-5-carboxylates 7a, 7b, 7c, 7d, 7e and 8f, 8g, 8h, 8i, 8j, 8k, 8l, 8m, 8n, 8o, 8p, 8q, 8r were synthesized, and their structures were confirmed by IR, 1H-NMR, MS spectra and elemental analysis. The results of preliminary bioassays show that some of the title compounds exhibit moderate to good herbicidal activities. Compared with the fluorine free compounds 7a, 7b, and 7e, the compounds bearing fluorine 8g, 8j, and 8q s...

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