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Visible-Light-Driven Copper-Catalyzed C(sp3)–O Cross-Coupling of Benzylic Radicals with Phenols

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成果类型:
期刊论文
作者:
Yu, Xiao-Ye;Chen, Jun;Chen, Hong-Wei;Xiao, Wen-Jing;Chen, Jia-Rong*
通讯作者:
Chen, Jia-Rong
作者机构:
[Xiao, Wen-Jing; Chen, Jun; Chen, Jia-Rong; Yu, Xiao-Ye; Chen, Hong-Wei] Cent China Normal Univ, Hubei Int Sci & Technol Cooperat Base Pesticide &, CCNU uOttawa Joint Res Ctr, Key Lab Pesticides & Chem Biol,Minist Educ,Coll C, Wuhan 430079, Peoples R China.
[Xiao, Wen-Jing] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China.
通讯机构:
[Chen, Jia-Rong] C
Cent China Normal Univ, Hubei Int Sci & Technol Cooperat Base Pesticide &, CCNU uOttawa Joint Res Ctr, Key Lab Pesticides & Chem Biol,Minist Educ,Coll C, Wuhan 430079, Peoples R China.
语种:
英文
期刊:
Organic Letters
ISSN:
1523-7060
年:
2020
卷:
22
期:
6
页码:
2333-2338
基金类别:
NNSFCNational Natural Science Foundation of China [21971081, 91856119, 21622201, 21820102003, 91956201, 21772053]; Science and Technology Department of Hubei Province [2017AHB047]; Program of Introducing Talents of Discipline to Universities of China (111 Program) [B17019]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A visible-light-driven, copper-catalyzed C(sp(3))-O coupling of benzylic radicals with phenols is described for the first time. This operationally simple and robust process features mild conditions, broad scope, and high functional-group tolerance, enabling the construction of a diverse range of cyanoalkylated aryl ethers (33 examples). Key to this protocol is the dual role of copper salt that acts not only as a phot...

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