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A cascade coupling strategy for one-pot total synthesis of β-carboline and isoquinoline-containing natural products and derivatives

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成果类型:
期刊论文
作者:
Zhu, Yan-Ping;Liu, Mei-Cai;Cai, Qun;Jia, Feng-Cheng;Wu, An-Xin*吴安心
通讯作者:
Wu, An-Xin(吴安心
作者机构:
[Wu, An-Xin; Jia, Feng-Cheng; Cai, Qun; Liu, Mei-Cai; Zhu, Yan-Ping] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan, Peoples R China.
通讯机构:
[Wu, An-Xin] C
Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan, Peoples R China.
语种:
英文
关键词:
carboline;cascade reactions;C?H coupling;isoquinoline;natural products
期刊:
Chemistry - A European Journal
ISSN:
0947-6539
年:
2013
卷:
19
期:
31
页码:
10132-10137
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21032001, 21272085]; PCSIRTProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT0953]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
Multi-birds with one stone: A cascade coupling strategy was developed for the synthesis of β-carbolines. The method can direct the synthesis of β-carboline and isoquinoline-containing natural products with high yields. Moreover, this protocol can also be further applied towards the total synthesis of natural products fascaplysin and papaverin (see scheme). Copyright ©...

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