版权说明 操作指南
首页 > 成果 > 详情

Design, syntheses and 3D-QSAR studies of novel N-phenyl pyrrolidin-2-ones and N-phenyl-1H-pyrrol-2-ones as protoporphyrinogen oxidase inhibitors

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Zhang, Li;Tan, Yin;Wang, Neng-Xue;Wu, Qiong-You;Xi, Zhen*;...
通讯作者:
Xi, Zhen
作者机构:
[Yang, Guang-Fu; Wang, Neng-Xue; Wu, Qiong-You; Zhang, Li; Tan, Yin] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Peoples R China.
[Xi, Zhen] Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.
通讯机构:
[Xi, Zhen] N
Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China.
语种:
英文
关键词:
Protoporphyrinogen oxidase;Herbicide;N-Phenyl pyrrolidin-2-one;N-Phenyl-1H-pyrrol-2-one;CoMFA
期刊:
Bioorganic & Medicinal Chemistry
ISSN:
0968-0896
年:
2010
卷:
18
期:
22
页码:
7948-7956
基金类别:
National Basic Research Program of ChinaNational Basic Research Program of China [2010CB126103]; NSFCNational Natural Science Foundation of China (NSFC) [20925206, 20932005, 21002038]; PCSIRTProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT0953]
机构署名:
本校为第一机构
院系归属:
化学学院
摘要:
The characteristics of low application rates, good crop selectivity, low residue and environmental safety exhibited by Protoporphyrinogen oxidase (PPO, EC 1.3.3.4)-inhibiting herbicides have attracted a world-wide research interests. As continuation of our research work on the development of new PPO inhibitors, a series of mono-carbonyl analogues of cyclic imides, N-phenyl pyrrolidin-2-ones and N-phenyl-1H-pyrrol-2-ones, were designed and synthesized based on previously established DFT-QSAR results. The PPO inhibition activities of 29 newly syn...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com