作者机构：
[Chen, Bizhong; Yao, Liangshuang] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Sun, Xiaojun] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Huang, Xuan] Beijing Normal Univ, Fac Psychol, Beijing, Peoples R China.;[Sun, Xiaojun; Sun, XJ] Cent China Normal Univ CCNU, Sch Psychol, 382 Xiongchu Rd, Wuhan 430079, Peoples R China.
通讯机构：
[Sun, XJ ] C;Cent China Normal Univ CCNU, Sch Psychol, 382 Xiongchu Rd, Wuhan 430079, Peoples R China.
关键词：
social anxiety;social relationships;longitudinal studies;meta-analysis
摘要：
It is theoretically plausible that social anxiety (SA) and social relationships (SR) can influence each other. However, the available empirical evidence is inconsistent, leading to substantial uncertainty regarding the cross-lagged relations between SA and SR. This meta-analysis systematically integrates data from 107 longitudinal studies, comprising 110 independent samples and involving a total of 115,133 participants from childhood to adulthood. Four types of SR were assessed: family-related, school-related, romantic, and general relationships. One-stage meta-analytic structural equation modeling was applied to fit four cross-lagged panel models and to test potential moderators. No significant publication bias was detected. Effect size analyses revealed that prior SA significantly and negatively predicted quality of all types of SR. Family-related and general relationships each predicted prospective SA symptoms, but school-related and romantic relationships did not. No moderators were identified in analyses of family-related and romantic relationships. However, the publication year, sample age, gender, reporter, and time lag played a moderating role in analyses of school-related and general relationships. These findings suggest that SA is a crucial factor undermining SR and that dysfunctional family and general relationships also contribute to the exacerbation of SA symptoms. The strengths, limitations, and future directions of this study are discussed. Public Significance Statement A hotly debated issue in academia is whether past social anxiety (SA) hinders future social relationships(SR) or if prior poor SR precipitate subsequent SA symptoms. To shed light on this matter, a comprehensive meta-analysis was conducted, encompassing data from 107 longitudinal studies and involving over 110,000 participants. The findings suggest that SA poses a significant risk to all types of SR, but only family-related and general relationships potentially impacted later levels of SA.
期刊：
BRIEFINGS IN BIOINFORMATICS,2024年25(2) ISSN：1467-5463
通讯作者：
Yunjie Zhao<&wdkj&>Yunhui Peng
作者机构：
[Xu, Wang; Peng, Yunhui; Zhang, Houfang; Zhao, Yunjie] Institute of Biophysics and Department of Physics, Central China Normal University, Wuhan 430079, China;[Guo, Wenhan] Computational Science Program, University of Texas at El Paso, El Paso, TX 79902, USA;[Jiang, Lijun] Hubei Key Laboratory of Genetic Regulation & Integrative Biology, School of Life Sciences, Central China Normal University, Wuhan 430079, China
通讯机构：
[Yunjie Zhao; Yunhui Peng] I;Institute of Biophysics and Department of Physics, Central China Normal University , Wuhan 430079 , China
关键词：
epigenetic regulation;histone cancer mutation;histone/nucleosome interaction;interaction network;nucleosome binding mode
摘要：
Nucleosomes represent hubs in chromatin organization and gene regulation and interact with a plethora of chromatin factors through different modes. In addition, alterations in histone proteins such as cancer mutations and post-translational modifications have profound effects on histone/nucleosome interactions. To elucidate the principles of histone interactions and the effects of those alterations, we developed histone interactomes for comprehensive mapping of histone-histone interactions (HHIs), histone-DNA interactions (HDIs), histone-partner interactions (HPIs) and DNA-partner interactions (DPIs) of 37 organisms, which contains a total of 3808 HPIs from 2544 binding proteins and 339 HHIs, 100 HDIs and 142 DPIs across 110 histone variants. With the developed networks, we explored histone interactions at different levels of granularities (protein-, domain- and residue-level) and performed systematic analysis on histone interactions at a large scale. Our analyses have characterized the preferred binding hotspots on both nucleosomal/linker DNA and histone octamer and unraveled diverse binding modes between nucleosome and different classes of binding partners. Last, to understand the impact of histone cancer-associated mutations on histone/nucleosome interactions, we complied one comprehensive cancer mutation dataset including 7940 cancer-associated histone mutations and further mapped those mutations onto 419,125 histone interactions at the residue level. Our quantitative analyses point to histone cancer-associated mutations' strongly disruptive effects on HHIs, HDIs and HPIs. We have further predicted 57 recurrent histone cancer mutations that have large effects on histone/nucleosome interactions and may have driver status in oncogenesis.
作者机构：
[Nie, Yufeng] Institute of Psychology and Behavior, Henan University, Jinming Avenue, Kaifeng, Henan Province, China;[Nie, Yufeng] Key Laboratory of Adolescent Cyberpsychology and Behavior of Ministry of Education, School of Psychology, Central China Normal University, Wuhan, China;[Pan, Ting] Key Laboratory of Adolescent Cyberpsychology and Behavior of Ministry of Education, School of Psychology, Central China Normal University, Wuhan, China;[He, Jinbo] Key Laboratory of Adolescent Cyberpsychology and Behavior of Ministry of Education, School of Psychology, Central China Normal University, Wuhan, China. Electronic address: hjb@mail.ccnu.edu.cn;[Li, Yongxin] Institute of Psychology and Behavior, Henan University, Jinming Avenue, Kaifeng, Henan Province, China. Electronic address: liyongxin@henu.edu.cn
关键词：
Face perception;Internet gaming disorder;N170;Reward positivity;Social reward
摘要：
Previous research has found that individuals with Internet gaming disorder (IGD) show different patterns of social function impairments in game-related and real-life social contexts. Impaired social reward processing may be the underlying mechanism according to the Social Motivation Theory. Thus, in this study, event-related potentials were recorded from 24 individuals with IGD and 24 healthy gamers during a social judgement task. We focused on reward positivity (RewP) elicited by game-related and real-life social rewards, and N170 elicited by game avatar faces and real faces. These indicators were used to explore the neurocognitive mechanism of impaired social reward processing in individuals with IGD and its relationship with early face perception. Results showed that (1) the RewP elicited by real-life social reward was considerably reduced in individuals with IGD relative to healthy gamers. (2) The N170 elicited by game avatar faces in individuals with IGD was larger than that elicited by real faces. However, the N170 was not associated with RewP in either group. (3) The score for IGD severity was correlated with the RewP elicited by real-life social reward and the N170 elicited by game avatar face. In conclusion, the present study suggests that the impaired social reward processing in individuals with IGD is mainly manifested in a decreased neural sensitivity to real-life social reward. Meanwhile, the reduced RewP elicited by real-life social reward and the enhanced N170 elicited by game avatar face might serve as potential biomarkers for IGD.
摘要：
Divergent thinking is assumed to benefit from releasing the constraint of existing knowledge (i.e. top-down control) and enriching free association (i.e. bottom-up processing). However, whether functional antagonism between top-down control-related and bottom-up processing-related brain structures is conducive to generating original ideas is largely unknown. This study was designed to investigate the effect of functional antagonism between the left inferior frontal gyrus and the right temporoparietal junction on divergent thinking performance. A within-subjects design was adopted for three experiments. A total of 114 participants performed divergent thinking tasks after receiving transcranial direct current stimulation over target regions. In particular, cathodal stimulation over the left inferior frontal gyrus and anodal stimulation over the right inferior frontal gyrus (Experiment 1), anodal stimulation over the right temporoparietal junction (Experiment 2), and both cathodal stimulation over the left inferior frontal gyrus and anodal stimulation over the right temporoparietal junction (Experiment 3) were manipulated. Compared with sham stimulation, the combination of hyperpolarization of the left inferior frontal gyrus and depolarization of the right temporoparietal junction comprehensively promoted the fluency, flexibility, and originality of divergent thinking without decreasing the rationality of generated ideas. Functional antagonism between the left inferior frontal gyrus (hyperpolarization) and right temporoparietal junction (depolarization) has a "1 + 1 > 2" superposition effect on divergent thinking.
期刊：
European Journal of Psychotraumatology,2024年15(1):2301844 ISSN：2000-8198
通讯作者：
Zhou, XQ
作者机构：
[Zhou, Xinqi] Sichuan Normal Univ, Inst Brain & Psychol Sci, Chengdu, Peoples R China.;[Meng, Yayun] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Li, Jiarui] Sichuan Southwest Vocat Coll Civil Aviat, Chengdu, Peoples R China.;[Shen, Xi] Southwest Univ, Fac Psychol, Ctr Mental Hlth Educ, Chongqing, Peoples R China.;[Zhou, Xinqi] Sichuan Normal Univ, Inst Brain & Psychol Sci, Chengdu 610066, Peoples R China.
通讯机构：
[Zhou, XQ ] S;Sichuan Normal Univ, Inst Brain & Psychol Sci, Chengdu 610066, Peoples R China.
关键词：
Mente divagada;Mind wandering;adversidad infantil;childhood adversity;cognitive flexibility;efecto de mediación en serie;flexibilidad cognitiva;habitual tendencies;serial mediation effect;tendencias habituales
摘要：
Background: Initial evidence proposes that exposure to childhood adversity may induce avoidance or withdrawal behaviour. However, it remains unclear whether childhood adversity results in avoidance from externally directed thinking to both deliberate and spontaneous mind wandering, i.e. intentionally or unintentionally diverting attention from ongoing task to task-independent thoughts.Objective: To assess the associations between childhood adversity, and mind wandering, and to evaluate the mediating roles of cognitive flexibility, and habit tendencies.Methods: A total of 601 Chinese subjects (378 females, Mage = 19.37) participated in the current study. The participants completed a series of questionnaires including demographics, childhood maltreatment, cognitive flexibility, habitual tendencies, and mind wandering.Results: Hierarchical regression analyses showed childhood adversity, the control facet of cognitive flexibility, and the automaticity facet of habitual tendencies had significant contributions to deliberate mind wandering (beta = 0.10, beta = -0.40, and beta = 0.06) and spontaneous mind wandering (beta = 0.09, beta = -0.28, and beta = 0.07). Serial mediation analyses revealed that the control and automaticity partially mediated associations between childhood adversity and mind wandering (deliberate mind wandering: 95% CIs = [0.037 0.078], and spontaneous mind wandering: 95% CIs = [0.023, 0.062]).Conclusions: The findings underscore the pivotal role of mediators in delineating the relationship between childhood adversity and mind wandering in everyday life. Interventions geared toward augmenting the control component of cognitive flexibility and regulating the automatic component of habitual tendencies show the potential to ameliorate the propensity of individuals affected by childhood adversity to disengage cognitively from the present moment. Individuals with greater childhood adversity have higher deliberate and spontaneous mind wandering.Low control and high automaticity contribute to mind wandering.The control and automaticity partially mediate the associations between childhood adversity and mind wandering. Antecedentes: La evidencia inicial propone que la exposicion a la adversidad infantil puede inducir conductas de evitacion o retraimiento. Sin embargo, aun no esta claro si la adversidad infantil da como resultado la evitacion del pensamiento dirigido externamente a la divagacion mental tanto deliberada como espontanea, es decir, desviar intencionalmente o no la atencion de la tarea en curso hacia pensamientos independientes de la tarea.Objetivo: Evaluar las asociaciones entre la adversidad infantil y la divagacion mental, y evaluar las funciones mediadoras de la flexibilidad cognitiva y las tendencias de los habitos.Metodos: Un total de 601 sujetos chinos (378 mujeres, Medad = 19.37) participaron en el estudio actual. Los participantes completaron una serie de cuestionarios que incluian datos demograficos, maltrato infantil, flexibilidad cognitiva, tendencias habituales y distracciones mentales.Resultados: Los analisis de regresion jerarquica mostraron que la adversidad infantil, la faceta de control de la flexibilidad cognitiva y la faceta de automaticidad de las tendencias habituales tuvieron contribuciones significativas a la divagacion mental deliberada (beta = 0.10, beta = -0.40 y beta = 0.06) y a la divagacion mental espontanea (beta = 0.09, beta = -0.28 y beta = 0.07). Los analisis de mediacion en serie revelaron que el control y la automaticidad mediaron parcialmente las asociaciones entre la adversidad infantil y la divagacion mental (divagacion mental deliberada: IC del 95% = [0.037, 0.078], y divagacion mental espontanea: IC del 95% = [0.023, 0.062]).Conclusiones: Los hallazgos subrayan el papel fundamental de los mediadores a la hora de delinear la relacion entre la adversidad infantil y la divagacion mental en la vida cotidiana. Las intervenciones orientadas a aumentar el componente de control de la flexibilidad cognitiva y regular el componente automatico de las tendencias habituales muestran el potencial de mejorar la propension de los individuos afectados por la adversidad infantil a desconectarse cognitivamente del momento presente.
通讯机构：
[Ding, XF ] C;Cent China Normal Univ CCNU, Sch Psychol, Wuhan 430079, Peoples R China.
摘要：
Previous evolutionary perspectives proposed that the space-time mapping on the sagittal axis originates from visuo-locomotion coupling when walking/running forward. Accordingly, the congenitally blind could not have developed a sagittal mental timeline if the latter depends on such a visuo-locomotion coupling. However, this conclusion was reached in only a single empirical study (Rinaldi et al. in J Exp Psychol General 147:444-450, 2018), and its theoretical underpinnings are not entirely convincing as locally static and continuous auditory input undergoes a relatively similar change as function of self-locomotion, but this type of sensory-locomotion coupling is spared even in congenital blindness. Therefore, the present study systematically explored whether the congenitally blind show space-time mappings on the sagittal axis using different paradigms in three experiments. In Experiment 1, using a typical implicit RT task, the congenitally blind showed the same preferred space-time mapping in the sagittal dimension as normally sighted participants did. In Experiment 2, this space-time mapping occurred even automatically when temporal relations were task-irrelevant in a naming task. In Experiment 3, in an explicit space-time mapping task, the congenitally blind were more likely to locate the past behind and the future in front of their bodies. Moreover, most blind participants used spatial metaphors for their space-time mapping on the sagittal axis. These results supported the conclusion that the congenitally blind have a sagittal mental timeline, and that their sensory-locomotion coupling experience was either more similar to that of sighted participants or not critical for the space-time mapping. The present study, thus, also helps to clarify the origin of the sagittal mental timeline.
期刊：
Journal of Youth and Adolescence,2024年53(1):1-20 ISSN：0047-2891
通讯作者：
Zhang, L
作者机构：
[Liang, Heting; Cai, Zhihui; Xiong, Fen; Zhang, Lin] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Liang, Heting; Cai, Zhihui; Xiong, Fen; Zhang, Lin] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan, Peoples R China.;[Liang, Heting; Cai, Zhihui; Xiong, Fen; Zhang, Lin] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.;[Bjureberg, Johan] Karolinska Inst, Ctr Psychiat Res, Stockholm Cty Council, Stockholm, Sweden.;[Bjureberg, Johan] Stockholm Cty Council, Stockholm Hlth Care Serv, Stockholm, Sweden.
通讯机构：
[Zhang, L ] C;Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan, Peoples R China.;Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.
关键词：
Emotion recognition;Internalizing problems;Children and adolescents;Moderation;Three-level meta-analysis
摘要：
Numerous studies have explored the link between how well youth recognize emotions and their internalizing problems, but a consensus remains elusive. This study used a three-level meta-analysis model to quantitatively synthesize the findings of existing studies to assess the relationship. A moderation analysis was also conducted to explore the sources of research heterogeneity. Through a systematic literature search, a total of 42 studies with 201 effect sizes were retrieved for the current meta-analysis, and 7579 participants were included. Emotion recognition was negatively correlated with internalizing problems. Children and adolescents with weaker emotion recognition skills were more likely to have internalizing problems. In addition, this meta-analysis found that publication year had a significant moderating effect. The correlation between emotion recognition and internalizing problems decreased over time. The degree of internalizing problems was also found to be a significant moderator. The correlation between emotion recognition and internalizing disorders was higher than the correlation between emotion recognition and internalizing symptoms. Deficits in emotion recognition might be relevant for the development and/or maintenance of internalizing problems in children and adolescents. The overall effect was small and future research should explore the clinical relevance of the association.
作者：
Peng, Yunhui;Song, Wei;Teif, Vladimir B.;Ovcharenko, Ivan;Landsman, David;...
期刊：
ELIFE,2024年12 ISSN：2050-084X
通讯作者：
Peng, YH;Panchenko, AR
作者机构：
[Peng, Yunhui; Peng, YH] Cent China Normal Univ, Inst Biophys, Wuhan, Peoples R China.;[Peng, Yunhui; Peng, YH] Cent China Normal Univ, Dept Phys, Wuhan, Peoples R China.;[Ovcharenko, Ivan; Landsman, David; Peng, Yunhui; Peng, YH; Song, Wei] NIH, Natl Lib Med, Bethesda, MD 20892 USA.;[Teif, Vladimir B.] Univ Essex, Sch Life Sci, Wivenhoe Pk, Colchester, England.;[Panchenko, Anna R.; Panchenko, AR] Queens Univ, Dept Pathol & Mol Med, Kingston, ON, Canada.
通讯机构：
[Peng, YH ] C;[Panchenko, AR ] Q;Cent China Normal Univ, Inst Biophys, Wuhan, Peoples R China.;Cent China Normal Univ, Dept Phys, Wuhan, Peoples R China.;NIH, Natl Lib Med, Bethesda, MD 20892 USA.
摘要：
Wrapping of DNA into nucleosomes restricts accessibility to DNA and may affect the recognition of binding motifs by transcription factors. A certain class of transcription factors, the pioneer transcription factors, can specifically recognize their DNA binding sites on nucleosomes, initiate local chromatin opening, and facilitate the binding of co-factors in a cell-type-specific manner. For the majority of human pioneer transcription factors, the locations of their binding sites, mechanisms of binding, and regulation remain unknown. We have developed a computational method to predict the cell-type-specific ability of transcription factors to bind nucleosomes by integrating ChIP-seq, MNase-seq, and DNase-seq data with details of nucleosome structure. We have demonstrated the ability of our approach in discriminating pioneer from canonical transcription factors and predicted new potential pioneer transcription factors in H1, K562, HepG2, and HeLa-S3 cell lines. Last, we systematically analyzed the interaction modes between various pioneer transcription factors and detected several clusters of distinctive binding sites on nucleosomal DNA.
作者机构：
[Sun, Cuicui] Sichuan Normal Univ, Sch Psychol, 5 Jingan Rd, Chengdu 610068, Peoples R China.;[Liu, Guanxiong; Zhou, Zhijin; Wang, Minqing] Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Peoples R China.;[Zhou, Xinqi] Sichuan Normal Univ, Inst Brain & Psychol Sci, 5 Jingan Rd, Chengdu 610068, Peoples R China.
通讯机构：
[Zhijin Zhou] S;School of Psychology, Central China Normal University, Wuhan, China
摘要：
Humor is a lubricant of interpersonal relationships and is regarded as an important quality of individual creativity. Previous studies have mainly focused on passive humor appreciation and comprehension but ignored active humor generation, especially the cognitive process of humor generation. Based on the hypothesis that humor generation is similar to creative cognition, this study used humorous two-part allegorical sayings to explore whether humor generation involves the cognitive processes of the activation and inhibition of information. The experiment manipulated the duration (5/10s) of the presentation of the first part of humorous two-part allegorical sayings, which are called "yinyu," and the type of subthreshold probe words (humorous probe words/usual probe words). The results showed that the interaction between the duration of the presentation of yinyu and the type of subthreshold probe words was significant; the correct number of humorous probe words reported was significantly lower than that of usual probe words when the yinyu was presented for 5s, which reflected the widespread activation of information. The correct number of humorous probe words reported was significantly higher than that of usual probe words when the yinyu was presented for 10s, which suggested the inhibition of non-humorous information. This study revealed the dynamic cognitive processes of humor generation and verified possible cognitive similarities between humor generation and creative cognition.
期刊：
Journal of Research on Adolescence,2023年33(3):828-840 ISSN：1050-8392
通讯作者：
Jianzhong Hong
作者机构：
[Bao, Guanghua; Xie, Han; Hong, Jianzhong; Zhang, Rui; Gao, Fangfang] Cent China Normal Univ, Sch Psychol, Key Lab Adolescent Cyberpsychol & Behav, Minist Educ, Wuhan, Peoples R China.;[Bao, Guanghua] Guangxi Univ Finance & Econ, Sch Finance & Insurance, Nanning, Peoples R China.;[Gao, Fangfang] Changzhi Univ, Dept Educ, Changzhi, Peoples R China.;[Hong, Jianzhong] Cent China Normal Univ, Sch Psychol, 152 Luo Yu Rd, Wuhan 430079, Peoples R China.
通讯机构：
[Jianzhong Hong] K;Key Laboratory of Adolescent Cyberpsychology and Behavior (Ministry of Education), School of Psychology, Central China Normal University, Wuhan, China
关键词：
Chinese emerging adults;conceptions of adulthood;parenting
摘要：
Framed through family life course theory, two studies were conducted to examine the relationship between parenting and Chinese emerging adults' conceptions of adulthood. Study 1 identified five important adult criteria among 763 participants (M(age) =23.13; 54.8% girls) through exploratory factor analysis. In Study 2, 616 participants (M(age) =22.51; 71.6% girls) completed measures of parental autonomy support (PAS) and psychological control (PPC), subjective adult status, and adult criteria. Results showed that PAS was positively associated with subjective adult status and endorsement of almost all adult criteria, whereas PPC was both positively and negatively associated with different adult criteria. Findings reveal the influence of family factors on youth transition to adulthood in the Chinese context and may have implications for family based interventions.
摘要：
BACKGROUND: Physical activity (PA) may prevent depressive symptoms, however, PA fluctuations may have different effects. Using three waves of nationally representative data, this study aimed to examine the effects of PA fluctuations on depressive symptoms. METHODS: Participants comprised 7633 adults free of depressive symptoms at the first two waves (M(age)=45.26, 54.70% males). They completed the China Family Panel Study in 2016 (T1), 2018 (T2), and 2020 (T3), respectively. Depressive symptoms were measured by the Center for Epidemiologic Studies Depression (CES-D) scale using a cutoff of 16. Participants' PA levels were split into regular PA or infrequent PA groups. Changes in PA levels between T1 and T2 were classified into four groups: maintained infrequent PA, initiated regular PA, ceased regular PA, and persisted regular PA. RESULTS: The incidence of depressive symptoms was 20.22% (19.05% possible and 1.17% severe depression). After multivariate adjustment, Poisson regression showed that persistent regular PA had 17.8% (95% CI: 0.724, 0.934) lower risks of incident depressive symptoms compared to maintained infrequent PA. And adults who ceased regular PA were more likely to experience depressive symptoms than those who persisted in regular PA (RR=1.188, 95% CI: 1.010, 1.398). LIMITATIONS: All items were self-reported. CES-D only examined self-diagnosed depressive symptoms, not medical diagnoses. CONCLUSION: Adults who persisted in regular PA may have a lower possibility of developing depressive symptoms. The finding might serve as an empirical reference to depression prevention.
摘要：
The Word Superiority Effect (WSE) refers to the phenomenon where a single letter is recognized more accurately when presented within a word, compared to when it is presented alone or in a random string. However, previous research has produced conflicting findings regarding whether this effect also occurs in the processing of Chinese characters. The current study employed the capacity coefficient, a measure derived from the Systems Factorial Technology framework, to investigate processing efficiency and test for the superiority effect in Chinese characters and English words. We hypothesized that WSE would result in more efficient processing of characters/words compared to their individual components, as reflected by super capacity processing. However, contrary to our predictions, results from both the "same" (Experiment 1) and "different" (Experiment 2) judgment tasks revealed that native Chinese speakers exhibited limited processing capacity (inefficiency) for both English words and Chinese characters. In addition, results supported an English WSE with participants integrating English words and pseudowords more efficiently than nonwords, and decomposing nonwords more efficiently than words and pseudowords. In contrast, no superiority effect was observed for Chinese characters. To conclude, the current work suggests that the superiority effect only applies to English processing efficiency with specific context rules and does not extend to Chinese characters.
期刊：
Journal of Affective Disorders,2023年323:444-451 ISSN：0165-0327
通讯作者：
Zhihong Ren
作者机构：
[Ren, Zhihong; Tong, Jingqiang; Zhang, Lin; Lai, Lizu] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Ren, Zhihong; Tong, Jingqiang; Zhang, Lin; Lai, Lizu] Minist Educ, Key Lab Adolescent CyberPsychol & Behav CCNU, Wuhan, Peoples R China.;[Xiang, Yu-Tao] Univ Macau, Inst Translat Med, Fac Hlth Sci, Unit Psychiat, Macau, Peoples R China.;[Xiang, Yu-Tao] Univ Macau, Ctr Cognit & Brain Sci, Macau, Peoples R China.;[Ren, Zhihong; Tong, Jingqiang; Zhang, Lin; Lai, Lizu] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.
通讯机构：
[Zhihong Ren] S;School of Psychology, Central China Normal University, China<&wdkj&>Key Laboratory of Adolescent CyberPsychology and Behavior(CCNU), Ministry of Education, Wuhan, China<&wdkj&>Key Laboratory of Human Development and Mental Health of Hubei Province, China
摘要：
BACKGROUND: The present study aimed to investigate the pandemic stage differences of mental health helpline help-seekers emotional responses, psychiatric symptoms, and related network structures during the COVID-19 pandemic in China. METHODS: The data was collected by a large-scale psychological helpline in response to the COVID-19 pandemic in mainland China. Counselor-reported information about the help-seekers pandemic-related emotional responses and psychiatric symptoms were recorded. A total of 26,870 callers' data from February 28, 2020, to April 23, 2021, were collected in the present study. A linear probability model and network analysis were conducted to determine the differences in help-seekers mental health concerns and network structures between the pandemic (stage I, from February 28, 2020, to April 28, 2020, N=9821) and the regular prevention and control period (stage II, from April 29, 2020, to April 23, 2021, N=17,049). RESULTS: Results revealed that anger, sadness, and obsession symptoms increased in stage II while symptoms of anxiety, somatization, and feelings of fear and stress were relieved. The network analysis results demonstrated both stage I and II networks centered on anxiety firmly. In stage II, the connection between anxiety and hypochondria and fear's strength centrality descended significantly. LIMITATIONS: The mental health outcomes of callers only included the counselor-reported data. CONCLUSIONS: The mental health concerns of helpline callers showed pandemic-related stage differences.
期刊：
Human Brain Mapping,2023年44(10):4040-4051 ISSN：1065-9471
通讯作者：
Yue-Jia Luo<&wdkj&>Jiang Qiu
作者机构：
[Qiu, Jiang; Chen, Hong; Zhou, Zheyi; Wei, Dongtao] Southwest Univ, Fac Psychol, Minist Educ, Key Lab Cognit & Personal, Chongqing, Peoples R China.;[Zuo, Xi-Nian; Qin, Shaozheng; Zhou, Zheyi; Luo, Yue-Jia] Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing, Peoples R China.;[Liu, Wei] Cent China Normal Univ, Sch Psychol, Wuhan, Peoples R China.;[Qin, Shaozheng] Beijing Normal Univ, Beijing Key Lab Brain Imaging & Connect, Beijing, Peoples R China.;[Zuo, Xi-Nian; Qin, Shaozheng] Beijing Normal Univ, McGovern Inst Brain Res, IDG, Beijing, Peoples R China.
通讯机构：
[Yue-Jia Luo] S;[Jiang Qiu] K;State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China<&wdkj&>Shenzhen Key Laboratory of Affective and Social Neuroscience, Magnetic Resonance Imaging Center, Center for Brain Disorders and Cognitive Sciences, Shenzhen University, Shenzhen, China<&wdkj&>Key Laboratory of Cognition and Personality of Ministry of Education, Faculty of Psychology, Southwest University, Chongqing, China<&wdkj&>Southwest University Branch, Collaborative Innovation Center of Assessment Toward Basic Education Quality, Beijing Normal University, Beijing, China
摘要：
The cognitive and behavioral development of children and adolescents is closely related to the maturation of brain morphology. Although the trajectory of brain development has been depicted in detail, the underlying biological mechanism of normal cortical morphological development in childhood and adolescence remains unclear. By combining the Allen Human Brain Atlas dataset with two single-site magnetic resonance imaging data including 427 and 733 subjects from China and the United States, respectively, we performed partial least squares regression and enrichment analysis to explore the relationship between the gene transcriptional expression and the development of cortical thickness in childhood and adolescence. We found that the spatial model of normal cortical thinning during childhood and adolescence is associated with genes expressed predominantly in astrocytes, microglia, excitatory and inhibitory neurons. Top cortical development-related genes are enriched for energy-related and DNA-related terms and are associated with psychological and cognitive disorders. Interestingly, there is a great deal of similarity between the findings derived from the two single-site datasets. This fills the gap between early cortical development and transcriptomes, which promotes an integrative understanding of the potential biological neural mechanisms.
摘要：
With the ever-changing social environment, individual creativity is facing a severe challenge induced by stress. However, little is known regarding the underlying mechanisms by which acute stress affects creative cognitive processing. The current research explored the impacts of the neuroendocrine response on creativity under stress and its underlying cognitive flexibility mechanisms. The enzyme-linked immuno sorbent assay was employed to assess salivary cortisol, which acted as a marker of stress-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis. Eye blink rate (EBR) and pupil diameter were measured as respective indicators of dopamine and noradrenaline released by the activation of the sympathetic-adrenal-medullary (SAM) axis. The Wisconsin card task (WCST) measured cognitive flexibility, while the alternative uses task (AUT) and the remote association task (RAT) measured separately divergent and convergent thinking in creativity. Results showed higher cortisol increments following acute stress induction in the stress group than control group. Ocular results showed that the stress manipulation significantly increased EBR and pupil diameter compared to controls, reflecting increased SAM activity. Further analysis revealed that stress-released cortisol impaired the originality component of the AUT, reducing cognitive flexibility as measured by perseverative errors on the WCST task. Serial mediation analyses showed that both EBR and pupil diameter were also associated with increased perseverative errors leading to poor originality on the AUT. These findings confirm that physiological arousal under stress can impair divergent thinking through the regulation of different neuroendocrine pathways, in which the deterioration of flexible switching plays an important mediating role. The current research is the first attempt to uncover the potential cognitive and neurophysiological mechanisms underlying creative processing under acute stress, providing a novel route to reducing stress and stress-related physiology. Moreover, the Dual Pathway to Creativity Model has been corroborated and extended for application in stressful situations.
作者：
Wang, Difan;Lin, Bingyan;Xiong, Fen;Deng, Yu;Zhang, Lin
期刊：
Journal of Affective Disorders,2023年341:319-328 ISSN：0165-0327
通讯作者：
Zhang, L
作者机构：
[Xiong, Fen; Zhang, Lin; Wang, Difan] Cent China Normal Univ, Sch Psychol, Wuhan 430000, Peoples R China.;[Xiong, Fen; Zhang, Lin; Wang, Difan] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan, Peoples R China.;[Xiong, Fen; Zhang, Lin; Wang, Difan] Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.;[Wang, Difan] Chinese Peoples Liberat Army Gen Hosp, Med Coll, Psychol Counseling & Serv Ctr, Grad Sch,Dept Field Internal Med, Beijing, Peoples R China.;[Deng, Yu; Lin, Bingyan] Harbin Univ Sci & Technol, Sch Foreign Languages, Harbin, Peoples R China.
通讯机构：
[Zhang, L ] C;Cent China Normal Univ, Sch Psychol, Wuhan 430000, Peoples R China.
关键词：
Acceptance and commitment therapy;Internet-based self-help intervention;Mindfulness;Obsessive-compulsive symptoms;Psychological flexibility;Sleep quality
摘要：
Background: Frontline nurses suffered unprecedented mental distress during the COVID-19 pandemic. It's essential to explore new and more accessible alternatives to improve the availability of psychological treatments. This study aimed to investigate the influence of online self-help iACT linear intervention and iACT loop intervention on sleep quality (SQ), obsessive-compulsive symptoms (OCS), and psychological flexibility (PF) in nurses.Methods: A randomized controlled trial was conducted at a hospital in China. 602 participants were randomly assigned to the iACT linear intervention, iACT loop intervention, or wait list control group, and required to complete the questionnaires of OCS, PF and SQ. The linear mixed effects analysis (LMM) was used to analyze the impact of the intervention on outcome variables.Results: LMM analyses demonstrated that both two intervention had significant improvement on OCS (t = -38.235, p < 0.001), PF (t = 28.156, p < 0.001), as well as SQ (t = -16.336, p < 0.001). There were significant differences between the linear group and loop group on the PF in T2 (t = -8.271, p < 0.001), T3 (t = -8.366, p < 0.001), T4 (t = -8.302, p < 0.001), with the iACT loop model (Cohen's d = 1.652) showing a slight advantage over the iACT linear model (Cohen's d = 1.134).Conclusions: The findings indicate that two interventions positively impact OCS, PF, and SQ. Compared to the iACT linear psychotherapy model, the iACT loop model shows greater effectiveness in enhancing PF, making it helpful to promote significant improvements in psychotherapy planning.
摘要：
The current methods for measuring patient-reported outcomes for amphetamine (speed) craving have limitation ability to adapt to the needs of individual patients while maintaining consistency in their scores. This study aimed to investigate whether the 40-item Desires for Speed Questionnaire (DSQ) could be improved for assessing clinical subjects using computerized adaptive testing (CAT). A sample of 677 participants from four drug addiction treatment centers in China was utilized in the study. Two types of analysis were conducted using the response data. First, the psychometric properties of all items were evaluated to meet the requirements of CAT. Second, multiple CAT simulations were carried out using real response data. The results indicated that the CAT method, which only required a small number of items (50%-75%), produced results that were only slightly different from the full DSQ assessment in terms of measuring amphetamine craving and criterion validity. In conclusion, this study suggests that developing a DSQ CAT for clinical subjects is useful as it leads to more efficient measurement without compromising the reliability of the test outcomes. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
期刊：
Journal of Interpersonal Violence,2023年38(13-14):7911-7940 ISSN：0886-2605
通讯作者：
Yu, Quanlei;Zhang, Lin;Xiong, Qing
作者机构：
[Zheng, Xintong; Chen, Jianwen] Huazhong Univ Sci & Technol, Wuhan, Peoples R China.;[Li, Congcong; Yu, Quanlei] Cent China Normal Univ, Wuhan, Peoples R China.;[Yu, Quanlei] East China Normal Univ, Shanghai, Peoples R China.;[Yu, Quanlei] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Xiong, Qing] Jiangxi Univ Finance & Econ, Nanchang, Peoples R China.
通讯机构：
[Yu, Quanlei] C;[Zhang, Lin] S;[Xiong, Qing] J;Cent China Normal Univ, Sch Psychol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.;Shandong Univ Tradit Chinese Med, Changqing Univ Sci & Technol Pk, Sch Hlth, Jinan 250355, Shandong, Peoples R China.
关键词：
peer victimization;problematic Internet use;depression;humor;general strain theory
摘要：
With the increasing development of science and technology, the Internet has become an essential part of people's daily lives providing great convenience. However, the Internet also leads to problematic Internet use (PIU) among adolescents, which has attracted increasing attention from the academic community. Peer victimization is a pervasive stressor among adolescents and has been proven to lead to a series of mental health challenges. Although the association between peer victimization and PIU has been well documented, the underlying mechanism remains unclear. This study aimed to understand how and when peer victimization increases the risk of PIU among adolescents. Building on Agnew's general strain theory, this study hypothesized that depression mediates the relationship between peer victimization and PIU and humor moderates the mediating model. To examine these hypotheses, 469 middle school students were recruited to complete a series of questionnaires on peer victimization, depression, humor, and PIU. The results showed that depression partially mediated the relationship between peer victimization and PIU. A moderated mediation analysis indicated that humor moderated the indirect pathway, consistent with the reverse stress-buffering model, the relationship between peer victimization and depression was stronger for adolescents with high humor. However, the relationship between depression and PIU was weaker in adolescents with high humor, which is in line with the stress-buffering model. These findings could be of significance in understanding the underlying mechanism of PIU associated with peer victimization and provide a new perspective for preventing PIU among adolescents, especially those experiencing peer victimization. The limitations and considerations for future research are discussed.
作者机构：
[Lu, Chan] XiangYa School of Public Health, Central South University, Changsha, China. Electronic address: chanlu@csu.edu.cn;[Wang, Faming] Division of Animal and Human Health Engineering, Department of Biosystems, KU Leuven, Leuven, Belgium;[Liu, Zijing; Yang, Wenhui; Liao, Hongsen] XiangYa School of Public Health, Central South University, Changsha, China;[Li, Bin] School of Psychology, Central China Normal University, Wuhan, China
通讯机构：
[Lu, C.] X;XiangYa School of Public Health, China
关键词：
Childhood allergic rhinitis;Early life exposure;Particulate matters;Pregnancy;TRAP
摘要：
BACKGROUND: Despite mounting evidence linking allergic rhinitis (AR) to air pollution, it remains unclear which major air pollutant(s) and critical window(s) of exposure play important roles in children's AR. OBJECTIVE: To examine the effects of intrauterine and early postnatal exposure to outdoor air pollution on children with doctor-diagnosed allergic rhinitis (DDAR). METHODS: A retrospective cohort study involving 8689 kindergarten children was conducted in Changsha, China, from 2019 to 2020. A questionnaire survey was conducted to collect information on the health status of children and their family members, as well as their living habits and home environment. Personal exposure to daily outdoor air pollutants (PM(2.5), PM(2.5-10), PM(10), SO(2), NO(2), and CO) was estimated during 40 gestational weeks, three trimesters, the entire pregnancy, and the first year after birth. Multiple logistic regression models were used to assess the associations between air pollution and children's DDAR. RESULTS: Children's DDAR was associated with intrauterine CO exposure, with adjusted ORs (95% CI) of 1.18 (1.03-1.34) for each IQR increase in CO exposure. The second and third trimesters were critical windows for PM(2.5) and CO exposure in relation to DDAR. Furthermore, early postnatal exposure to PM(2.5-10) and PM(10) in first year of life was associated with DDAR development, with adjusted ORs (95% CI) of 1.11 (1.01-1.22) and 1.27 (1.09, 1.47). The entire pregnancy and the first year of life were critical windows for CO and PM(10) exposure. Some children were predisposed to DDAR risk due to exposure to traffic-related air pollution (TRAP). CONCLUSION: Our findings support the hypothesis of "fetal origin of allergic rhinitis" by demonstrating that intrauterine and early postnatal exposure to air pollution plays an important role in children's DDAR.
作者机构：
[Fu, Zhenrong; Zhou, Zongkui] Minist Educ, Key Lab Adolescent Cyberpsychol & Behav CCNU, Wuhan, Peoples R China.;[Fu, Zhenrong; Zhou, Zongkui] Cent China Normal Univ, Sch Psychol, Key Lab Human Dev & Mental Hlth Hubei Prov, Wuhan, Peoples R China.;[Zhao, Mingyan] Tangshan Gongren Hosp, Dept Psychol, Tangshan, Peoples R China.;[Li, Yuxia] Tangshan Cent Hosp, Dept Neurol, Tangshan, Peoples R China.;[Han, Ying; Li, Yuxia] Capital Med Univ, Dept Neurol, Xuanwu Hosp, Beijing, Peoples R China.
通讯机构：
[Han, Y ] C;[Li, SY ] B;Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Haikou 570228, Peoples R China.;Capital Med Univ, Dept Neurol, Xuanwu Hosp, Beijing 100053, Peoples R China.
摘要：
We empirically derived subgroups from the SILCODE SCD cohort using cluster analysis based on eight neuropsychological measures and examined patterns of structural and functional indices of each cluster‐derived subgroup relative to NC. Four SCD subgroups emerged: dysexecutive/mixed, neuropsychiatric, amnestic, and a cluster‐derived normal group. Abstract Aims We evaluated whether Subjective Cognitive Decline (SCD) subtypes could be empirically derived within the Sino Longitudinal Study on Cognitive Decline (SILCODE) SCD cohort and examined associated neuroimaging markers, biomarkers, and clinical outcomes. Methods A cluster analysis was performed on eight neuropsychological test scores from 124 SCD SILCODE participants and 57 normal control (NC) subjects. Structural and functional neuroimaging indices were used to evaluate the SCD subgroups. Results Four subtypes emerged: (1) dysexecutive/mixed SCD (n = 23), (2) neuropsychiatric SCD (n = 24), (3) amnestic SCD (n = 22), and (4) cluster‐derived normal (n = 55) who exhibited normal performance in neuropsychological tests. Compared with the NC group, each subgroup showed distinct patterns in gray matter (GM) volume and the amplitude of low‐frequency fluctuations (ALFF). Lower fractional anisotropy (FA) values were only found in the neuropsychiatric SCD group relative to NC. Conclusion The identification of empirically derived SCD subtypes demonstrates the presence of heterogeneity in SCD neuropsychological profiles. The cluster‐derived normal group may represent the majority of SCD individuals who do not show progressive cognitive decline; the dysexecutive/mixed SCD and amnestic SCD might represent high‐risk groups with progressing cognitive decline; and finally, the neuropsychiatric SCD may represent a new topic in SCD research.
