摘要:
Efficient rhodium(I)-catalyzed regioselective direct arylation and alkenylation of aromatic C-H bonds has been realized with aromatic carboxylic and cinnamic anhydrides as the coupling partners via decarbonylation and C-H activation under phosphine-free conditions.
期刊:
JOURNAL OF ORGANIC CHEMISTRY,2009年74(2):888-890 ISSN:0022-3263
通讯作者:
Xiao, Wen-Jin
作者机构:
[Xiao, Wen-Jin; Li, Chang-Feng] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.;[Li, Chang-Feng; Alper, Howard] Univ Ottawa, Dept Chem, Ctr Catalysis Res & Innovat, Ottawa, ON K1N 6N5, Canada.;[Xiao, Wen-Jin] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Xiao, Wen-Jin] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
摘要:
Palladium-catalyzed ring-opening thiocarbonylation of vinylcyclopropanes (VCPs) with thiols and carbon monoxide affords the corresponding unsaturated thioesters in moderate to excellent yields. This reaction provides a general method for the ring-opening thiocarbonylation of VCPs. It further demonstrates the utility of transition metal catalysts for the synthesis of organosulfur compounds.
期刊:
JOURNAL OF ORGANIC CHEMISTRY,2009年74(9):3532-3535 ISSN:0022-3263
通讯作者:
Xiao, Wen-Jing
作者机构:
[Chen, Cai-Bao; Wang, Xu-Fan; Cheng, Hong-Gang; Xiao, Wen-Jing; Cao, Yi-Ju] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.;[Xiao, Wen-Jing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Xiao, Wen-Jing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
摘要:
A Bronsted acid catalyzed tandem Diels-Alder/aromatization reaction of 2-vinylindoles has been developed. The reaction provides a highly efficient and concise approach to 3-indolyl-substituted tetrahydrocarbazoles with various substituents in high yields under mild conditions.
作者机构:
[Yang, Qian; Alper, Howard] Univ Ottawa, Dept Chem, Ctr Catalysis Res & Innovat, Ottawa, ON K1N 6N5, Canada.;[Yang, Qian; Lai, Yuan-Yuan; Xiao, Wen-Jing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.;[Alper, Howard] Univ Ottawa, Dept Chem, Ctr Catalysis Res & Innovat, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada.
通讯机构:
[Alper, Howard] U;Univ Ottawa, Dept Chem, Ctr Catalysis Res & Innovat, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada.
摘要:
The ring-closing enyne metathesis reaction of alkyl 2-substituted-2-(N-alkynyl acrylamido)esters using the first-generation Grubbs’ catalyst afforded five-membered lactams bearing a 1,3-diene moiety in high isolated yields. In the reaction process, the presence of ethylene gas is essential.
期刊:
JOURNAL OF ORGANIC CHEMISTRY,2008年73(15):6006-6009 ISSN:0022-3263
通讯作者:
Xiao, Wen-Jing
作者机构:
[Wang, Xu-Fan; Xiao, Wen-Jing; Chen, Jia-Rong; An, Xiao-Lei; Zhu, Xiao-Yu] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hebei, Peoples R China.;[Xiao, Wen-Jing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hebei, Peoples R China.
通讯机构:
[Xiao, Wen-Jing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hebei, Peoples R China.
摘要:
A new class of organocatalysts has been designed by rational combination of proline with cinchona alkaloids. The chiral amine 3a, prepared from l-proline and cinchonidine, has been found to be an efficient catalyst for the direct aldol reactions of acetone or 2-butanone with a wide range of aldehydes (up to 98% ee). The cinchonidine backbone is essential to the reaction efficiency and enantioselectivity.
作者机构:
[Wang, Hongli; Xiao, Wenjing; Zhang, Bin; Wu, Hong; Xu, Wenyuan] Cent China Normal Univ, Dept Chem, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Wang, Hongli] C;Cent China Normal Univ, Dept Chem, Wuhan 430079, Hubei, Peoples R China.
摘要:
In the title compound, C19H15NO, the N atom adopts an approximately trigonal-planar geometry, lying 0.07 (1) Å from the plane defined by its three neighbouring C atoms. The two phenyl rings and the benzaldehyde group form dihedral angles of 53.0 (1)/47.2 (1) and 29.0 (1)°, respectively, with this central plane.
通讯机构:
[Xiao, Wen-Jing] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.
摘要:
The first organocatalytic oxa-Diels–Alder reaction of acyclic α,β–unsaturated ketones with aldehydes is described. This reaction represents a highly chemo- and diastereoselective synthesis of substituted tetrahydropyran-4-ones in good yields with dr up to >95:5.
作者机构:
Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, 152 Luoyu Road, Wuhan, Hubei 430079, China, Fax: (+86) 27‐6786‐2041 http://chem‐xiao.ccnu.edu.cn/default.aspx
作者机构:
[Liu, Hiu; Li, Chang-Feng; Xiao, Wen-Jing; Liao, Jie; Cao, Yi-Ju; Liu, Xiao-Peng] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.;[Li, Chang-Feng] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Li, Chang-Feng] C;Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
摘要:
An enantioselective organocatalytic intramolecular ring-closing Friedel-Crafts-type alkylation of indolyl alpha,beta-unsaturated aldehydes has been developed. This powerful new strategy allows enantioselective access to THPIs and THBCs in a straightforward and atom-economical manner.
摘要:
An operationally trivial and environmentally benign procedure for direct Michael addition has been developed. The reaction of various ketones with nitroolefins can be performed in water to afford the corresponding nitro compounds in high yields in the presence of a pyrrolidine-thiourea organocatalyst at 35 degrees C. The reaction exhibits a high stereoselectivity, with high enantioselectivities (up to 99%) as well as diastereoselectivities (up to 99:1) being achieved under the optimal conditions. (c) 2006 Elsevier Ltd. All rights reserved.