Respiratory chain succinate-ubiquinone oxidoreductase (SQR or complex II) and ubihydroquinonecytochrome (cyt) c oxidoreductase (cyt bc(1) or complex III) have been demonstrated as the promising targets of numerous antibiotics and fungicides. As a continuation of our research work on the development of new fungicides, a series of 1,2,4-triazole-1,3-disulfonamide derivatives with dual functions targeting both SQR and cyt bc(1) were designed and synthesized by coupling diverse diphenyl ether moieties with triazolesulfonamide units. These newly synthesized compounds were characterized by elemental...
