National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21572075]; 111 ProjectMinistry of Education, China - 111 Project [B17019]
机构署名：
本校为第一且通讯机构
院系归属：
化学学院
摘要：
A new efficient synthesis of pyrrolidin-2-ones via sequential Wittig reaction/nucleophilic addition/cyclization was developed. The Wittig reaction of the phosphoranes with isocyanates produced ketenimine intermediates that were then treated with primary amines to give amidines, which were treated with catalytic sodium alkoxide to give 2-imino-5-oxopy...
