期刊论文

Xiao, Wen-Jing

英文

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

0002-7863

2017

139

36

12847-12854

10.1021/jacs.7b08207

We thank the National Natural Science Foundation of China (nos. 21472057, 21472058, 21572074, 21622201, and 21772052), the Program of Introducing Talents of Discipline to Universities of China (111 Program, B17019), the Foundation for the Author of National Excellent Doctoral Dissertation of PR China (no. 201422), and Outstanding Youth Foundation of Hubei Province (2015CFA033) for support of this research. Prof. Dr. Fang-Fang Pan is sincerely acknowledged for X-ray crystallography and helpful discussion about the structure of chiral copper catalyst. This paper is dedicated to Professor Qi-Lin Zhou on the occasion of his 60th birthday.

本校为第一且通讯机构

The Wittig reaction, which produces alkenes from phosphorus ylides (P-ylides) and carbonyls, is one of the most powerful tools in chemical synthesis. This Nobel Prize-winning reaction is widely used in natural product synthesis, fine chemical production (i.e., medicines and agricultural agents), and polymer functionalization. Despite these great achievements, the potential of the Wittig reaction, particularly regarding the access of chiral alkene building blocks, has not been fully exploited. The main area that requires additional exploration i...