The cell cycle phase distributions of Hz-AM1 cells grown in monolayer culture were G(1) = 49.7 +/- 3.3%, S = 22.7 +/- 3.8% and G(2)/M = 27.8 +/- 4.2% without >4N DNA content. The culture doubling time was about 40 h and the duration of the G(1), S and G(2)/M phases was estimated to be 10, 14 and 16 h, respectively. HaSNPV infection of Hz-AM1 cells resulted in both unsynchronized and synchronized G, phase arrest at G(2)/M phase. HaSNPV infection also resulted in the appearance of more than 4N DNA content, which accumulated to the highest levels 72 h post-infection. We also found that the expres...
