期刊论文、会议论文

Fung, Wing Kam

英文

Communications in Statistics - Simulation and Computation

0361-0918

2016

45

7

2362-2376

1st Meeting of y-BIS / 1st Meeting of jSPE

JUL 23-26, 2012

Caparica, PORTUGAL

[Pan, Dong-Dong] Yunnan Univ, Dept Stat, Kunming, Peoples R China.^[Li, Zheng-Bang] Cent China Normal Univ, Sch Math & Stat, Wuhan, Peoples R China.^[Li, Qi-Zhai] Chinese Acad Sci, Acad Math & Syst Sci, Beijing, Peoples R China.^[Fung, Wing Kam] Univ Hong Kong, Dept Stat & Actuarial Sci, Hong Kong, Hong Kong, Peoples R China.

530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA

TAYLOR & FRANCIS INC

10.1080/03610918.2014.901360

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [11225103, 11301465, 11371353, 11401240, 11471135, 61134013]; Youth Program of Applied Basic Research Programs of Yunnan Province [2013FD001]; Foundation of Yunnan University [2012CG018]; Foundation of Central China Normal University [CCNU13A05032]; Young and Middle-aged Teachers Training Program of Yunnan University [XT412003]

本校为其他机构

In genome-wide association studies (GWASs) to detect the disease-associated genetic variants, two-stage design has received much attention because of its cost effectiveness and high efficiency. Under the framework of a two-stage design, it has been shown that joint analysis is more powerful than replication-based analysis. Several robust tests have been proposed for joint analysis to handle the problem of unknown genetic mode of inheritance. However, existing joint analysis of combining test statistics from both stages might suffer from a loss ...