The stability, electronic and magnetic properties, and reactivity of icosahedral M Co12 clusters are studied using the discrete variational local-spin-density-functional method, where M=Ti, V, Cr, Mn, Fe, Co, and Ni. By means of the binding-energy calculation, we obtained the M-Co bond length of the clusters and compared their relative stability. We calculated the electronic structure of the clusters in their equilibrium configurations. The calculated results show that all the clusters have metallic character, and that the clusters with M being Ti, Mn, or Co have closed electronic shells while...