Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Zhu, Biran;Lei, Lei;Fu, Kaiyu;Zhao, Songlin;Hua, Jianghuan;...

通讯作者：

Jian Han

作者机构：

[Zhu, Biran; Hua, Jianghuan] Hubei Univ Chinese Med, Sch Basic Med Sci, Wuhan 430065, Peoples R China.

[Zhou, Bingsheng; Zhu, Biran; Yang, Lihua; Fu, Kaiyu; Lei, Lei; Han, Jian] Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China.

[Zhao, Songlin] Cent China Normal Univ, Inst Nanosci & Nanotechnol, Coll Phys Sci & Technol, Wuhan 430079, Peoples R China.

[Li, Rui] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.

通讯机构：

[Jian Han] S

State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China

语种：

英文

关键词：

Chorion;Co-exposure;Neurotoxicity;SiO(2) nanoparticles;Tetrabromobisphenol A

期刊：

Science of The Total Environment

ISSN：

0048-9697

年：

2022

卷：

845

页码：

157364

DOI：

10.1016/j.scitotenv.2022.157364

基金类别：

CRediT authorship contribution statement Biran Zhu: Investigation, Writing - Original Draft. Lei Lei: Methodology, Formal analysis. Kaiyu Fu: Writing editing. Songlin Zhao: SEM-EDS. Jianghuan Hua: Visualization. Lihua Yang: Writing-review & editing. Jian Han: Investigation, Writing-review & editing, Supervision. Rui Li: Writing-review & editing. Bingsheng Zhou: Conceptualization, acquisition, Project administration.

机构署名：

本校为其他机构

院系归属：

物理科学与技术学院

生命科学学院

摘要：

Silicon dioxide nanoparticles (n-SiO(2)) absorb tetrabromobisphenol A (TBBPA) and modify its bioavailability and toxicity in the aquatic phase; embryonic chorion is an efficient barrier against nanoparticles (e.g., SiO(2)) and influences their toxicity. However, few studies have investigated developmental neurotoxicity in fish after co-exposure to TBBPA and n-SiO(2), especially considering the barrier function of the chorion. In the present study, zebrafish embryos were exposed to TBBPA (50, 100, and 200 μg/L) alone or in combination with n-Si...

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Neurotoxicity of tetrabromobisphenol A and SiO2 nanoparticle co-exposure in zebrafish and barrier function of the embryonic chorion

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