Current advancements and future perspectives of long noncoding RNAs in lipid metabolism and signaling

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Duan, Jiufei;Huang, Zhao;Nice, Edouard C.;Xie, Na*;Chen, Mingqing;...

通讯作者：

Xie, Na;Huang, CH;Chen, MQ

作者机构：

[Huang, Canhua; Xie, Na; Huang, CH; Duan, Jiufei; Huang, Zhao] West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China.

[Huang, Canhua; Xie, Na; Huang, CH; Duan, Jiufei; Huang, Zhao] West China Hosp, Canc Ctr, Chengdu 610041, Peoples R China.

[Huang, Canhua; Xie, Na; Huang, CH; Duan, Jiufei; Huang, Zhao] Sichuan Univ, West China Sch Basic Med Sci & Forens Med, Chengdu 610041, Peoples R China.

[Huang, Canhua; Xie, Na; Huang, CH; Duan, Jiufei; Huang, Zhao] Collaborat Innovat Ctr Biotherapy, Chengdu 610041, Peoples R China.

[Nice, Edouard C.] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic, Australia.

通讯机构：

[Chen, MQ ] C

[Xie, N; Huang, CH ] W

West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China.

West China Hosp, Canc Ctr, Chengdu 610041, Peoples R China.

Sichuan Univ, West China Sch Basic Med Sci & Forens Med, Chengdu 610041, Peoples R China.

语种：

英文

关键词：

Long noncoding RNAs;Lipid metabolism;Lipid chaperones;Lipid receptors;Therapeutic target

期刊：

Journal of Advanced Research

ISSN：

2090-1232

年：

2023

卷：

页码：

105-123

DOI：

10.1016/j.jare.2022.08.007

基金类别：

National Key Research and Devel-opment Project of China [2020YFA0509400, 2020YFC2002705]; Guangdong Basic and Applied Basic Research Foundation [2019B030302012]; 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University [ZYGD22007, ZYJC21004]; Chinese NSFC [82130082, 81821002, 81790251, 82103168]

机构署名：

本校为通讯机构

院系归属：

生命科学学院

摘要：

Background: The investigation of lncRNAs has provided a novel perspective for elucidating mechanisms underlying diverse physiological and pathological processes. Compelling evidence has revealed an intrin-sic link between lncRNAs and lipid metabolism, demonstrating that lncRNAs-induced disruption of lipid metabolism and signaling contribute to the development of multiple cancers and some other diseases, including obesity, fatty liver disease, and cardiovascular disease.Aimof Review: The current review summarizes the recent advances in basic research about lipid metabo-lism and lipid signaling-...

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Current advancements and future perspectives of long noncoding RNAs in lipid metabolism and signaling

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