FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes

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成果类型：

期刊论文

作者：

Li, Jianghuai;Ma, Yuemin;Yuan, Wanli;Xiao, Yutao;Liu, Chenxi;...

通讯作者：

Yang, Yongbo;Liu, Kaiyu;Bravo, Alejandra

作者机构：

[Yuan, Wanli; Liu, Kaiyu; Yang, Yongbo; Liu, KY; Peng, Jianxin; Wang, Jia; Peng, Rong; Li, Jianghuai; Ma, Yuemin] Cent China Normal Univ, Inst Entomol, Sch Life Sci, Wuhan 430079, Hubei, Peoples R China.

[Xiao, Yutao] Chinese Acad Agr Sci, Agr Genom Inst Shenzhen, Shenzhen 518120, Peoples R China.

[Liu, Chenxi] Chinese Acad Agr Sci, State Key Lab Biol Plant Dis & Insect Pests, West Yuanmingyuan Rd, Beijing 100193, Peoples R China.

[Soberon, Mario; Bravo, Alejandra] Univ Nacl Autonoma Mexico, Inst Biotecnol, Apdo Postal 510-3, Cuernavaca 62250, Morelos, Mexico.

通讯机构：

[Yang, YB; Liu, KY] C

[Bravo, Alejandra] U

Cent China Normal Univ, Inst Entomol, Sch Life Sci, Wuhan 430079, Hubei, Peoples R China.

Univ Nacl Autonoma Mexico, Inst Biotecnol, Apdo Postal 510-3, Cuernavaca 62250, Morelos, Mexico.

语种：

英文

关键词：

*ATP binding cassette;*Bacillus thuringiensis;*FOXA;*Toxin receptor;*Transcription factor

期刊：

Insect Biochemistry and Molecular Biology

ISSN：

0965-1748

年：

2017

卷：

页码：

1-11

DOI：

10.1016/j.ibmb.2017.07.004

基金类别：

National Key R&D Program of China [2017YFD0200400]

机构署名：

本校为第一且通讯机构

院系归属：

生命科学学院

摘要：

Cry toxins produced by Bacillus thuringiensis (Bt) are insecticidal proteins widely used in insect control. Recently, it was shown that ATP-binding cassette transporter proteins (ABC) such as ABCC2, ABCC3, ABCG1 and ABCA2 are implicated in the insecticidal action of Cry toxins as putative receptors. However, the transcriptional regulators involved in the expression of ABC transporter genes remain unknown. Sequence analysis of promoter regions of ABCC2 gene from Helicoverpa armigera and ABCC3 gene from Spodoptera litura Sl-HP cultured cells, rev...

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FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes

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