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Exploratory analysis of human microbiome by linear and nonlinear methods

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成果类型:
期刊论文
作者:
Xingpeng Jiang(蒋兴鹏);Xiaohua Hu;Weiwei Xu;Tingting He(何婷婷
作者机构:
[Weiwei Xu] Wuhan University
[Xingpeng Jiang; Xiaohua Hu] Drexel University
[Tingting He] Central China Normal University
语种:
英文
关键词:
human microbiomemultidimensional scaling analysisnonnegative matrix factorizationprinciple component analysist-distributed stochastic neighbor embedding
期刊:
ACM SIGBioinformatics Record
ISSN:
2331-9291
年:
2013
卷:
3
期:
1
页码:
10–17
机构署名:
本校为第一机构
摘要:
There is a growing recognition that the human microbiome - microbes living in intimate association with us - forms a vital part of our biology, and plays an important role in both health and sickness. A huge amount of data are being generated about these communities, much through metagenomics methods, which sequence DNA without directly identifying which organisms they come from. These data pose a tremendous opportunity for understanding, and a tremendous computational and theoretical challenge. In this paper, we compare several linear and nonlinear methods to explore human microbiome. There i...

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