Engineered Metallacycle-Based Supramolecular Photosensitizers for Effective Photodynamic Therapy

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Le Tu;Chonglu Li;Prof. Xiaoxing Xiong;Ji Hyeon Kim;Qian Li;...

通讯作者：

Prof. Jong Seung Kim<&wdkj&>Prof. Yao Sun<&wdkj&>Prof. Jong Seung Kim Prof. Jong Seung Kim Prof. Jong Seung Kim<&wdkj&>Prof. Yao Sun Prof. Yao Sun Prof. Yao Sun

作者机构：

[Le Tu; Chonglu Li; Longcan Mei; Prof. Junrong Li; Prof. Yao Sun; Le Tu Le Tu Le Tu; Chonglu Li Chonglu Li Chonglu Li; Longcan Mei Longcan Mei Longcan Mei; Prof. Junrong Li Prof. Junrong Li Prof. Junrong Li; Prof. Yao Sun Prof. Yao Sun Prof. Yao Sun] National Key Laboratory of Green Pesticide, College of Chemistry, Central China Normal University, Wuhan, 430079 China

[Prof. Xiaoxing Xiong; Prof. Xiaoxing Xiong Prof. Xiaoxing Xiong Prof. Xiaoxing Xiong] Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, 430060 China

[Ji Hyeon Kim; Prof. Jong Seung Kim; Ji Hyeon Kim Ji Hyeon Kim Ji Hyeon Kim; Prof. Jong Seung Kim Prof. Jong Seung Kim Prof. Jong Seung Kim] Department of Chemistry, Korea University, Seoul, 02841 Korea

[Qian Li; Qian Li Qian Li Qian Li] Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, Qingdao University of Science & Technology, Qingdao, 266100 China

[Prof. Shuang Liu; Prof. Shuang Liu Prof. Shuang Liu Prof. Shuang Liu] School of Materials Science and Engineering, Wuhan University of Technology, Wuhan, 430070 China

通讯机构：

[Prof. Jong Seung Kim; Prof. Jong Seung Kim Prof. Jong Seung Kim Prof. Jong Seung Kim] D

[Prof. Yao Sun; Prof. Yao Sun Prof. Yao Sun Prof. Yao Sun] N

National Key Laboratory of Green Pesticide, College of Chemistry, Central China Normal University, Wuhan, 430079 China<&wdkj&>Department of Chemistry, Korea University, Seoul, 02841 Korea

语种：

英文

关键词：

Anticancer;Molecular Engineering;Photodynamic Therapy;RuII Metallacycle;Supramolecular Chemistry

期刊：

Angewandte Chemie

ISSN：

0044-8249

年：

2023

卷：

135

期：

页码：

e202301560-

DOI：

10.1002/ange.202301560

机构署名：

本校为第一且通讯机构

院系归属：

化学学院

摘要：

Although metallacycle-based supramolecular photosensitizers (PSs) have attracted increasing attention in biomedicine, their clinical translation is still hindered by their inherent dark toxicity. Herein, we report what to our knowledge is the first example of a molecular engineering approach to building blocks of metallacycles for constructing a series of supramolecular PSs (RuA–RuD), with the aim of simultaneously reducing dark toxicity and enhancing phototoxicity, and consequently obtaining high phototoxicity indexes (PI). Detailed in vitro ...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Engineered Metallacycle-Based Supramolecular Photosensitizers for Effective Photodynamic Therapy

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问