Let X be a coherent configuration associated with a transitive group G. In terms of the intersection numbers of X, a necessary condition for the point stabilizer of G to be a TI-subgroup, is established. Furthermore, under this condition, X is determined up to isomorphism by the intersection numbers. It is also proved that asymptotically, this condition is also sufficient. More precisely, an arbitrary homogeneous coherent configuration satisfying this condition is associated with a transitive group, the point stabilizer of which is a TI-subgroup. As a byproduct of the developed theory, recent ...