Long-Term Impairment of Sound Processing in the Auditory Midbrain by Daily Short-Term Exposure to Moderate Noise

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成果类型：

期刊论文

作者：

Cheng, Liang;Wang, Shao-Hui;Peng, Kang;Liao, Xiao-Mei*

通讯作者：

Liao, Xiao-Mei

作者机构：

[Peng, Kang; Wang, Shao-Hui; Liao, Xiao-Mei; Cheng, Liang] Cent China Normal Univ, Sch Life Sci, Wuhan 430079, Peoples R China.

[Peng, Kang; Wang, Shao-Hui; Liao, Xiao-Mei; Cheng, Liang] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.

[Cheng, Liang] Cent China Normal Univ, Sch Psychol, Wuhan 430079, Peoples R China.

[Cheng, Liang] Cent China Normal Univ, Minist Educ, Key Lab Adolescent Cyberpsychol & Behav, Wuhan 430079, Peoples R China.

[Cheng, Liang] Cent China Normal Univ, Inst Publ Hlth & Mol Med Anal, Wuhan 430079, Peoples R China.

通讯机构：

[Liao, Xiao-Mei] C

Cent China Normal Univ, Sch Life Sci, Wuhan 430079, Peoples R China.

Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.

语种：

英文

期刊：

Neural Plasticity

ISSN：

2090-5904

年：

2017

卷：

2017

页码：

3026749

DOI：

10.1155/2017/3026749

基金类别：

National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31300914]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2013M531719, 2014T70716]; CCNU of MOE [CCNU16JCZX11, CCNU15A02024, CCNU15A02029]

机构署名：

本校为第一且通讯机构

院系归属：

生命科学学院

心理学院

摘要：

Most citizen people are exposed daily to environmental noise at moderate levels with a short duration. The aim of the present study was to determine the effects of daily short-term exposure to moderate noise on sound level processing in the auditory midbrain. Sound processing properties of auditory midbrain neurons were recorded in anesthetized mice exposed to moderate noise (80 dB SPL, 2 h/d for 6 weeks) and were compared with those from age-matched controls. Neurons in exposed mice had a higher minimum threshold and maximum response intensity, a longer first spike latency, and a higher slope...

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Long-Term Impairment of Sound Processing in the Auditory Midbrain by Daily Short-Term Exposure to Moderate Noise

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