Aerobic exercise attenuates high-fat diet-induced renal injury through kidney metabolite modulation in mice

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成果类型：

期刊论文

作者：

Xiong, Yingzhe;Luan, Yisheng;Yuan, Lingfeng;Hong, Weihao;Wang, Bin;...

通讯作者：

Zhao, H;Zhang, B

作者机构：

[Xiong, Yingzhe; Wang, Bin; Zhao, Hua] Cent China Normal Univ, Sch Phys Educ & Sports, Wuhan, Peoples R China.

[Xiong, Yingzhe; Zhang, Bing; Hong, Weihao; Luan, Yisheng; Yuan, Lingfeng] Tsinghua Univ, Div Sports Sci & Phys Educ, Beijing, Peoples R China.

[Zhao, Hua] Cent China Normal Univ, Sch Phys Educ & Sports, Wuhan 430079, Peoples R China.

[Zhang, B; Zhang, Bing] Tsinghua Univ, Div Sports Sci & Phys Educ, Beijing 100084, Peoples R China.

通讯机构：

[Zhao, H ] C

[Zhang, B ] T

Cent China Normal Univ, Sch Phys Educ & Sports, Wuhan 430079, Peoples R China.

Tsinghua Univ, Div Sports Sci & Phys Educ, Beijing 100084, Peoples R China.

语种：

英文

关键词：

Aerobic exercise;prevention;obesity;renal injury;metabolomics

期刊：

Renal Failure

ISSN：

0886-022X

年：

2024

卷：

期：

页码：

2286330

DOI：

10.1080/0886022X.2023.2286330

基金类别：

Science and Technology Service Project of Winter Sports Management Center of General Administration of Sport of China [20212001045]; CCNU colleges' basic research and operation of MOE [CCNU23XJ033]

机构署名：

本校为第一且通讯机构

院系归属：

体育学院

摘要：

PURPOSE: To investigate the preventive effect of aerobic exercise on renal damage caused by obesity. METHODS: The mice in the Control (Con) and Control + Exercise (Con + Ex) groups received a standard chow diet for the 21-week duration of the study, while the High-fat diet (HFD) group and High-fat diet + Exercise (HFD + Ex) group were fed an HFD. Mice were acclimated to the laboratory for 1 week, given 12 weeks of being on their respective diets, and then the Con + Ex and HFD + Ex groups were subjected to moderate intensity aerobi...

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Aerobic exercise attenuates high-fat diet-induced renal injury through kidney metabolite modulation in mice

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