National Basic Research Program of China (973 Program)National Basic Research Program of China [2011CB504004]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31371275, 30971635]; Central China Normal University from the College's basic research and operation of Ministry of Education [CCNU14Z01003]
机构署名：
本校为第一且通讯机构
院系归属：
生命科学学院
摘要：
AbstractBackgroundGenome‐wide association studies (GWAS) of type 2 diabetes (T2D) have discovered a number of loci that contribute to susceptibility to the disease. Future challenges include elucidation of functional mechanisms through which these GWAS‐identified loci modulate T2D disease risk. The aim of the present study was to comprehensively characterize T2D associated single nucleotide polymorphisms (SNPs) and genes through computational approaches.MethodsComputational biology approaches used in the present study included comparative gen...
摘要(中文)：
Genome-wide association studies (GWAS) of type 2 diabetes (T2D) have discovered a number of loci that contribute to susceptibility to the disease. Future challenges include elucidation of functional mechanisms through which these GWAS-identified loci modulate T2D disease risk. The aim of the present study was to comprehensively characterize T2D associated single nucleotide polymorphisms (SNPs) and genes through computational approaches.
Computational biology approaches used in the present study included comparative genomic analyses and function...
