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Contribution of the transcription factor SfGATAe to Bt Cry toxin resistance in Spodoptera frugiperda through reduction of ABCC2 expression.

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成果类型:
期刊论文
作者:
Liu, Leilei*;He, Wenfeng;Xu, Peiwen;Wei, Wei;Wang, Jintao;...
通讯作者:
Liu, Leilei
作者机构:
[Liu, Leilei] Center of Applied Biotechnology, School of Life Sciences and Technology, Wuhan University of Bioengineering, Wuhan, Hubei, China. Electronic address: liulei@mails.ccnu.edu.cn
[Wang, Jintao; Xu, Peiwen; Wei, Wei; He, Wenfeng] Center of Applied Biotechnology, School of Life Sciences and Technology, Wuhan University of Bioengineering, Wuhan, Hubei, China
[Xu, Peiwen; He, Wenfeng] College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, Hubei, China
[Liu, Kaiyu] School of Life Sciences, Central China Normal University, Wuhan, Hubei, China
通讯机构:
[Liu, Leilei] C
Center of Applied Biotechnology, School of Life Sciences and Technology, Wuhan University of Bioengineering, Wuhan, Hubei, China. Electronic address:
语种:
英文
关键词:
Cry1Ac toxin;GATAe transcription factor;Spodoptera frugiperda
期刊:
International Journal of Biological Macromolecules
ISSN:
0141-8130
年:
2024
卷:
267
期:
Pt 1
页码:
131459
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Insect resistance evolution poses a significant threat to the advantages of biopesticides and transgenic crops utilizing insecticidal Cry-toxins from Bacillus thuringiensis (Bt). However, there is limited research on the relationship between transcriptional regulation of specific toxin receptors in lepidopteran insects and their resistance to Bt toxins. Here, we report the positive regulatory role of the SfGATAe transcription factor on the expression of the ABCC2 gene in Spodoptera frugiperda. DNA regions in the SfABCC2 promoter that are vital for regulation by SfGATAe, utilizing DAP-seq techn...

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