Ultrafast 2,7-Naphthyridine-Based fluorescent probe for detection of thiophenol with a remarkable Stokes shift and its application In vitro and in vivo

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成果类型：

期刊论文

作者：

Ren, Rui;Xu, Hong-Chuang;Dong, Huan;Peng, Hong-Tao;Wu, Pan-Pan;...

通讯作者：

She, Neng-Fang;Sun, Qi

作者机构：

[Ren, Rui; Peng, Hong-Tao; Wu, Pan-Pan; Dong, Huan; Xu, Hong-Chuang; She, Neng-Fang] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.

[Sun, Qi; Qiu, Yuan] Wuhan Inst Technol, Minist Educ, Key Lab Green Chem Proc, Wuhan 430205, Hubei, Peoples R China.

[Sun, Qi; Qiu, Yuan] Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Hubei, Peoples R China.

[Yan, Sheng-Gang] Guizhou Med Univ, Sch Pharmaceut Sci, Guiyang 550025, Guizhou, Peoples R China.

通讯机构：

[She, Neng-Fang] C

[Sun, Qi] W

Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, Wuhan 430079, Hubei, Peoples R China.

Wuhan Inst Technol, Minist Educ, Key Lab Green Chem Proc, Wuhan 430205, Hubei, Peoples R China.

Wuhan Inst Technol, Sch Chem & Environm Engn, Wuhan 430205, Hubei, Peoples R China.

语种：

英文

关键词：

2,7-Naphthyridine;Bioimaging;Fluorescent probe;Theoretical calculation;Zebrafish

期刊：

Talanta

ISSN：

0039-9140

年：

2019

卷：

205

页码：

120067

DOI：

10.1016/j.talanta.2019.06.067

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21272086, 21502063, 21804102]; Hubei Provincial Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [2016CFB262, 2017CFB222]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU19QN073]

机构署名：

本校为第一且通讯机构

院系归属：

化学学院

摘要：

2,7-Naphthyridine derivatives were developed as fluorophores for the first time to design two fluorescence probes, AND-DNP and ND-DNP, which can be applied for detecting thiophenol in aqueous media. Comparing with ND-DNP, AND-DNP showed more favorable properties such as lower background, larger Stokes shift, and higher fluorescence quantum yield for detecting thiophenol. Moreover, the experimental results were verified by theoretical calculations. Hence, AND-DNP was selected as the superior fluorescence probe to detect thiophenol because of its high sensitivity and selectivity. Based on the ex...

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Ultrafast 2,7-Naphthyridine-Based fluorescent probe for detection of thiophenol with a remarkable Stokes shift and its application In vitro and in vivo

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