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Iminocoumarin-based red to near-infrared fluorescent turn-on probe with a large Stokes shift for imaging H2S in living cells and animals

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成果类型:
期刊论文
作者:
Feng, Shumin;Xia, Qingfeng;Feng, Guoqiang*
通讯作者:
Feng, Guoqiang
作者机构:
[Feng, Guoqiang; Xia, Qingfeng; Feng, Shumin] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Feng, Guoqiang] C
Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
关键词:
Hydrogen sulfide;Iminocoumarin;Large Stokes shift;Living cells and animals;Near-infrared fluorescent probe
期刊:
Dyes and Pigments
ISSN:
0143-7208
年:
2019
卷:
163
页码:
447-453
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21672080]; 111 ProjectMinistry of Education, China - 111 Project [B17019]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
The development of organic dye-based fluorescent probes for detection of H2S in living systems has attracted considerable attention in recent years. In this work, a novel tetrahydroquinoxaline iminocoumarin-based red to near-infrared (red-to-NIR) fluorescent probe was developed for detection of H2S. This probe shows a rapid and distinct red-to-NIR fluorescent turn-on detection process for H2S with high selectivity and sensitivity (the detection limit was determined to be as low as 10 nM at physiological pH). In addition, this probe exhibits a r...

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