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Stem cells in lung repair and regeneration: Current applications and future promise

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成果类型:
期刊论文
作者:
Zhu, Yuqing;Chen, Xiao;Yang, Xu;El-Hashash, Ahmed*
通讯作者:
El-Hashash, Ahmed
作者机构:
[El-Hashash, Ahmed; Chen, Xiao; Zhu, Yuqing] Zhejiang Univ, Ctr Stem Cell & Regenerat Med, Sch Med, Hangzhou, Zhejiang, Peoples R China.
[El-Hashash, Ahmed; Chen, Xiao; Zhu, Yuqing] Zhejiang Univ, Ctr Stem Cell & Regenerat Med, Sch Basic Med, Hangzhou, Zhejiang, Peoples R China.
[Yang, Xu] Cent China Normal Univ, Sch Life Sci, Sect Environm Biomed, Wuhan, Hubei, Peoples R China.
[El-Hashash, Ahmed] Univ Edinburgh Zhejiang Univ Inst UoE ZJU Inst, Haining, Zhejiang, Peoples R China.
[El-Hashash, Ahmed] Univ Edinburgh, Edinburgh Med Sch, Edinburgh, Midlothian, Scotland.
通讯机构:
[El-Hashash, Ahmed] C
Care of Yang A, Edinburgh Med Sch, UoE ZJU Inst, Univ Edinburgh, Off 429,Zhejiang Int Campus,Arts & Sci Bldg, Haining 314400, Zhejiang, Peoples R China.
语种:
英文
关键词:
lung;regeneration;stem cells;tissue repair
期刊:
JOURNAL OF CELLULAR PHYSIOLOGY
ISSN:
0021-9541
年:
2018
卷:
233
期:
10
页码:
6414-6424
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
Lung diseases are major cause of morbidity and mortality worldwide. The progress in regenerative medicine and stem cell research in the lung are currently a fast-growing research topic that can provide solutions to these major health problems. Under normal conditions, the rate of cellular proliferation is relatively low in the lung in vivo, compared to other major organ systems. Lung injury leads to the activation of stem/progenitor cell populations that re-enter the cell cycle. Yet, little is known about stem cells in the lung, despite common thoughts that these cells could play a critical ro...

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