The main residue of the title compound, C18H22N6O6·C2H4Cl2, is a derivative of glycoluril. The six-membered heterocycle adopts a chair conformation and shares two N atoms with two five-membered rings of the glycoluril unit to form the flexible sidewalls of a mol-ecular clip. Two ethyl fragments and the solvent mol-ecule are disordered; the site occupancy factors for the ethyl groups are 0.72/0.28 and 0.75/0.25 and for the solvent molecule 0.54/0.46. Inter-molecular N - H⋯O and N - H⋯N hydrogen bonds link the cyclo-penta-[cd]indene mol-ecules...