Recent work published by Rovis, Schoenebeck, and co-workers in Nature Chemistry describes a synergistic CO 2 mediation and photocatalysis strategy for challenging α-alkylation of primary aliphatic amines by using quinuclidine as a hydrogen atom transfer (HAT) catalyst for γ-lactam synthesis. Electrostatic attraction between the in-situ-generated carbamate and quinuclidinium radical cation is critical for the selectivity. Recent work published by Rovis, Schoenebeck, and co-workers in Nature Chemistry describes a synergistic CO 2 mediation and ...
