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Glutathione transmembrane transmission gated by light-switches

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成果类型:
期刊论文
作者:
Wang, Yingqian;Gu, Yulin;Yang, Yuxia;Sun, Kunpeng*;Li, Haibing*
通讯作者:
Sun, Kunpeng;Li, Haibing
作者机构:
[Sun, Kunpeng; Wang, Yingqian; Gu, Yulin; Yang, Yuxia] Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou, Peoples R China.
[Wang, Yingqian; Li, Haibing] Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
通讯机构:
[Sun, Kunpeng; Li, Haibing] C
Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou, Peoples R China.
Cent China Normal Univ, Coll Chem, Minist Educ, Key Lab Pesticide & Chem Biol CCNU, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Light-responsive;Nanochannel;Glutathione transport;beta-cyclodextrin;Switches;Light-controlled
期刊:
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
ISSN:
1010-6030
年:
2021
卷:
405
页码:
112954
基金类别:
National Key Research and Development Program of China [2018YFD0200102]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21911530178, 21772055, 21572076]; 111 ProjectMinistry of Education, China - 111 Project [B17019]; CCNU from the colleges' basic research and operation of MOEMinistry of Education, Singapore
机构署名:
本校为通讯机构
院系归属:
化学学院
摘要:
Photoresponsive azobenzene-cyclodextrin light-switches fabricated artificial film which can be used to regulate the transmission of glutathione (GSH) across the membrane will gain much significance due to the important role of GSH in various biological process. In this work, we used azobenzene-cyclodextrin complex as switchable unit to manipulate gating transport. Under the control of ultraviolet (UV 365 nm) and visible (Vis 430 nm) light, two states of "ON" and "OFF" transport of GSH can be realized by the switches. This study achieved controlled molecule transport through channels by taking ...

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