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Oxidative damage caused by air formaldehyde exposure in organs of mice

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成果类型:
期刊论文、会议论文
作者:
Qiao, Y;Lu, ZS;Gan, YK;Yan, Y;Hou, LL;...
通讯作者:
Yang, X
作者机构:
[Qiao, Y; Lu, ZS; Yan, Y; Li, CM; Gan, YK; Hou, LL; Yang, X] Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
通讯机构:
[Yang, X] C
Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
formaldehyde;oxidative damage;SOD;GSK;MDA
期刊:
INDOOR AIR 2005: PROCEEDINGS OF THE 10TH INTERNATIONAL CONFERENCE ON INDOOR AIR QUALITY AND CLIMATE, VOLS 1-5
ISSN:
0908-5920
年:
2005
卷:
15
页码:
3813-3816
会议名称:
10th International Conference on Indoor Air Quality and Climate (Indoor Air 2005)
会议时间:
SEP 04-09, 2005
会议地点:
Beijing, PEOPLES R CHINA
会议主办单位:
Cent China Normal Univ, Coll Life Sci, Wuhan 430079, Peoples R China.
会议赞助商:
Tsinghua Univ, Minist Educ China, Natl Nat Sci Fdn China, Beijing Municipal Commiss Sci & Technol, Shanghai Municipal Commiss Sci & Technol, US EPA, Amer Ind Hyg Assoc, Amer Soc Heating, Refrigerating & Air Conditioning Engineers, Int Commiss Occupat Hlth, SC Indoor Air Qual & Hlth, Int Council Res & Innovat Bldg & Construct, European Commiss Asia Pro Eco Programme Promot Sustainable Solut Environm Europe & Asia, Korean Soc Indoor Environm, Soc Indoor Environm
主编:
Yang, X Zhao, B Zhao, R
出版地:
TSINGHUA UNIV HAIDIANQU, BEIJING 100084, PEOPLES R CHINA
出版者:
TSINGHUA UNIV PRESS
ISBN:
978-7-89494-830-4
机构署名:
本校为第一且通讯机构
院系归属:
生命科学学院
摘要:
Few researches concern about oxidative damage of inhaled formaldehyde in medium or low concentrations. Therefore, we treated three groups of mice with 1.0 mg/m(3) 3.0 mg/m(3) formaldehyde and the control group inhaled fresh air. All of the mice were treated 6 hours per day for 10 days. After exposure, the activities of total superoxide dismutase (SOD), content of glutathione (GSH) and malondialdehyde (MDA) in five organs-brain, heart, lung, liver and kidney were measured. The results showed that inhaled formaldehyde caused the obvious decrease of SOD activities in five organs (P

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