期刊论文、会议论文

Chen, Xin

英文

2011 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE (BIBM 2011)

2156-1125

2011

3-9

IEEE International Conference on Bioinformatics & Biomedicine (BIBM 2011)

2011 IEEE International Conference on Bioinformatics and Biomedicine

2011-01-01

Atlanta, Georgia, USA

[Chen, Xin;Hu, Xiaohua;An, Yuan] Drexel Univ, Coll Informat Sci & Technol, Philadelphia, PA 19104 USA.^[He, TingTing] Cent China Normal Univ, Dept Comp Sci, Wuhan, Hubei, Peoples R China.^[Wu, Xindong] Univ Vermont, Dept Comp Sci, Burlington, VT USA.

IEEE, IEEE Comp Soc

Wu, FX Zaki, M Morishita, S Pan, Y Wong, S Christianson, A Hu, X

10662 LOS VAQUEROS CIRCLE, PO BOX 3014, LOS ALAMITOS, CA 90720-1264 USA

IEEE COMPUTER SOC

978-0-7695-4574-5

10.1109/BIBM.2011.12

NSFCNational Natural Science Foundation of China (NSFC) [90920005]; [NSF CCF-0905337]; [NSF CCF 0905291]; [NSF CCF 1049864]

本校为其他机构

In this paper, based on the functional elements derived from non-redundant CDs catalogue, we show that the configuration of functional groups in meta-genome samples can be inferred by probabilistic topic modeling. The probabilistic topic modeling is a Bayesian method that is able to extract useful topical information from unlabeled data. When used to study microbial samples (assuming that relative abundance of functional elements is already obtained by a homology-based approach), each sample can be considered as a 'document', which has a mixture of functional groups, while each functional grou...