Ambient ozone, and urban PM2.5 co-exposure, aggravate allergic asthma via transient receptor potential vanilloid 1-mediated neurogenic inflammation

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Lian, Zongpei;Qi, Haomin;Liu, Xudong;Zhang, Yuchao;Xu, Ruijia;...

通讯作者：

Zeng, Y.;Li, J.

作者机构：

[Lian, Zongpei; Li, Jinquan; Qi, Haomin; Zeng, Yan; Xu, Ruijia] Wuhan Univ Sci & Technol, Brain Sci & Adv Technol Inst, Sch Med, Wuhan 430081, Peoples R China.

[Li, Jinquan; Qi, Haomin; Xu, Ruijia] Wuhan Univ Sci & Technol, Sch Med, Hubei Prov Key Lab Occupat Hazard Identificat & Co, Wuhan 430065, Peoples R China.

[Zhang, Yuchao; Liu, Xudong] Moutai Inst, Dept Food Sci & Engn, Renhuai 564507, Peoples R China.

[Yang, Xu] Cent China Normal Univ, Coll Life Sci, Sect Environm Biomed, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.

通讯机构：

[Zeng, Y.] B

[Li, J.] J

Brain Science and Advanced Technology Institute, School of Medicine, Wuhan University of Science and Technology, Wuhan 430081, China

语种：

英文

关键词：

Allergic asthma;Ozone;PM(2.5);Substance P;TRPV1

期刊：

Ecotoxicology and Environmental Safety

ISSN：

0147-6513

年：

2022

卷：

243

页码：

114000

DOI：

10.1016/j.ecoenv.2022.114000

基金类别：

This work was funded by National Natural Science Foundation of China (81903278), Guizhou Provincial Science and Technology Projects: Qiankehejichu-ZK[2022]yiban542 and Regular Undergraduate Institutions Nature Science Research Project of Guizhou Education Department (Technology top-notch talent support project QianjiaoheKYzi[2018]083). Thanks to Professor NahidAboutaleb, from Iran University of Medical Sciences, for giving us valuable help to revise the manuscript.

机构署名：

本校为其他机构

院系归属：

生命科学学院

摘要：

Allergic asthma is the most common pulmonary inflammatory disease, and epidemiological studies have revealed that PM2.5 or ambient ozone (O3) exposure contribute to the higher prevalence of allergic asthma. Current experimental evidence focus principally on the pathogenic effect of exposure to a single air pollutant, ignoring the possible synergistic effect of combined exposure to a mix of these pollutants, which is a more realistic scenario. In this study, allergic mice and a nociceptor antagonist were used to explore the mechanisms of co-expo...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Ambient ozone, and urban PM2.5 co-exposure, aggravate allergic asthma via transient receptor potential vanilloid 1-mediated neurogenic inflammation

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问