版权说明 操作指南
首页 > 成果 > 详情

Structure basis of non-structural protein pA151R from African Swine Fever Virus

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
Huang, Jian-Wen;Niu, Du;Liu, Ke;Wang, Qian;Ma, Lixin;...
通讯作者:
Yang, Yong;Guo, Rey-Ting
作者机构:
[Liu, Weidong; Zhang, Lilan; Niu, Du; Chen, Chun-Chi; Wu, Shan; Min, Jian; Ma, Lixin; Huang, Jian-Wen; Zhou, Shuyu; Yang, Yong; Guo, Rey-Ting; Wang, Qian] Hubei Univ, Hubei Collaborat Innovat Ctr Green Transformat Bi, Sch Life Sci, State Key Lab Biocatalysis & Enzyme Engn,Hubei Ke, Wuhan 430062, Peoples R China.
[Liu, Ke] Cent China Normal Univ, Sch Life Sci, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
通讯机构:
[Yang, Y; Guo, RT] H
Hubei Univ, Hubei Collaborat Innovat Ctr Green Transformat Bi, Sch Life Sci, State Key Lab Biocatalysis & Enzyme Engn,Hubei Ke, Wuhan 430062, Peoples R China.
语种:
英文
关键词:
African swine fever virus;pA151R;Thioredoxin;X-ray crystallography
期刊:
Biochemical and Biophysical Research Communications
ISSN:
0006-291X
年:
2020
卷:
532
期:
1
页码:
108-113
基金类别:
This work has been supported by the National Key Research and Development Program of China ( 2019YFA070030 ), the National Natural Science Foundation of China ( 31870790 , 31971205 and 31900930 ), China Postdoctoral Science foundation ( 2019M662572) . We thank NSRRC (National Synchrotron Radiation Research Center, Taiwan) for access to beam line TPS-05A that contributed for the synchrotron data collection.
机构署名:
本校为其他机构
院系归属:
生命科学学院
摘要:
African Swine Fever Virus (ASFV) is an enveloped double-stranded DNA icosahedral virus that causes the devastating hemorrhagic fever of pigs. ASFV infections severely impact swine production and cause an enormous economic loss, but no effective vaccine and therapeutic regimen is available. pA151R is a non-structural protein of ASFV, which is expressed at both early and late stages of viral infection. Significantly, pA151R may play a key role in ASFV replication and virus assembly as suppressing pA151R expression can reduce virus replication. Ho...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com