Detection of protein complexes and functional modules plays a crucial role for strengthening the comprehension of cellular organization and biological functions on the dynamic protein-protein interaction network. In this article, we put forward a new strategy to identify temporal protein complexes. Integrating time-course gene expression data into static protein interaction data, a series of time-sequenced subnetworks were constructed. Then we combined the network topology and gene ontology information for defining the distance between proteins in PPI network. A novel method to find the cluste...