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Transcriptome analysis provides insights into high fat diet-induced kidney injury and moderate intensity continuous training-mediated protective effects

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成果类型:
期刊论文
作者:
Hong, Weihao;Luan, Yisheng;Ma, Yixuan;Zhang, Bing;Xiong, Yingzhe
通讯作者:
Bing Zhang
作者机构:
[Zhang, Bing; Hong, Weihao; Luan, Yisheng; Ma, Yixuan] Division of Sports Science and Physical Education, Tsinghua University, Beijing, 100081, China
[Xiong, Yingzhe] School of Physical Education, Central China Normal University, Wuhan, 430079, China
通讯机构:
[Bing Zhang] D
Division of Sports Science and Physical Education, Tsinghua University, Beijing, 100081, China
语种:
英文
关键词:
Exercise;HFD;Kidney injury;MICT;Obesity;Transcriptome
期刊:
Heliyon
ISSN:
2405-8440
年:
2024
卷:
10
期:
5
页码:
e27157
机构署名:
本校为其他机构
院系归属:
体育学院
摘要:
Although physics exercise has been utilized to prevent and treat a variety of metabolic diseases, its role in obesity-related kidney diseases remains poorly understood. In this study, we assessed the protective potential of moderate intensity continuous training (MICT) against high fat diet (HFD)-induced kidney injury and found that MICT could significantly reduce obesity indexes (body weight, serum glucose, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol) and kidney injury indexes (serum creatinine ...

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