期刊论文

Fu, Liwu

英文

Bioorganic & Medicinal Chemistry Letters

0960-894X

2011

21

4

1102-1104

10.1016/j.bmcl.2010.12.130

National Basic Research Program of ChinaNational Basic Research Program of China [2010CB126100]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [20772042, 21002037]; Opening Foundation of the Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University [2009GDGP0101]; PCSIRTProgram for Changjiang Scholars & Innovative Research Team in University (PCSIRT) [IRT0953]

本校为第一机构

The synthesis and biological activity of 1,3-benzenedicarbonyl dithioureas are described. Bioassay results indicated that these compounds exhibited cytotoxicity against various cancer cells. For example, compounds 4a showed the best inhibition activities against KB and CNE2 with IC50 10.72 and 9.91 μM, respectively. ©...