期刊论文

Liu, Jinlin

英文

BMC Biotechnology

1472-6750

2015

15

1

1-11

10.1186/s12896-015-0199-8

We would like to thank Dr. Weicheng Bei (at College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China) and Dr. Pat Blackall (at Queensland Alliance for Agriculture and Food Innovation, UQ, Australia) for the generous donation of A. pleuropneumoniae strains. We thank Dr. Jinrong Min (at Chromatin Structural Biology and Epigenetics, University of Toronto, Toronto, Canada) for the prediction of protein structure. This research was supported by grants from the National Nature Science Foundation of China (31101820) and the Fundamental Research Funds for the Central Universities (CCNU15A05037).

本校为第一且通讯机构

Background: Actinobacillus pleuropneumoniae, a Gram-negative bacterium, is the causative agent of porcine pleuropneumonia, a highly contagious and often fatal disease. Because current vaccines confer limited protection against A. pleuropneumoniae infection, the development of more effective vaccines is urgently required. The identification of immunogenic and protective antigens, such as an outer-membrane lipoprotein, will advance this purpose. Results: Sixty putative lipoproteins were predicted from the genomic sequence of A. pleuropneumoniae u...