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Identification and analysis of retrogenes in the East Asian nematode Caenorhabditis sp. 5 genome

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成果类型:
期刊论文
作者:
Zhou, Kun;Zou, Ming;Duan, Mingyue;He, Shunping*;Wang, Guoxiu
通讯作者:
He, Shunping
作者机构:
[Zhou, Kun; Duan, Mingyue; Wang, Guoxiu] Cent China Normal Univ, Hubei Key Lab Genet Regulat & Integrat Biol, Wuhan 430079, Peoples R China.
[Zou, Ming] Huazhong Agr Univ, Wuhan 430070, Peoples R China.
[He, Shunping] Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China.
通讯机构:
[He, Shunping] C
Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China.
语种:
英文
关键词:
Caenorhabditis sp. 5;retrogenes;chimeric genes;genome;Caenorhabditis sp. 5;rétrogènes;gènes chimériques;génome
期刊:
GENOME
ISSN:
0831-2796
年:
2015
卷:
58
期:
7
页码:
349-355
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC); Hubei Key Laboratory of Genetic Regulation and Integrative Biology [31071998, GRIB201405]
机构署名:
本校为第一机构
院系归属:
生命科学学院
摘要:
Retroposition, a molecular mechanism generating new genes, helps the formation of retrogenes and new functions, contributing to the evolution of genomes. The completed genome sequence of Caenorhabditis sp. 5 presents an excellent opportunity to identify retrogenes within C. sp. 5. We identified a total of 43 retrogenes and their corresponding chimeric genes. Among these, 29 were found to be intact retrogenes and 14 to be retropseudogenes. Unexpectedly, a high number of retrogenes appear to be functional and possibly involved in catalysis. Also,...

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