https://orcid.org/0000-0002-2533-5187 Xiong Zhili panda20052005@126.com 1 2 https://orcid.org/0000-0002-4874-4186 Qu Shaocheng qushaocheng@mail.ccnu.edu.cn 1 Luo Jing 282503765@qq.com 1 Moysis Lazaros 1 Department of Electronics and Information Engineering Central China Normal University Wuhan 430079 China ccnu.edu.cn 2 School of Physics and Electric Information Huanggang Normal University Huanggang 438000 China hgnc.net 2019 19 12 2019 2019 19 05 2019 24 06 2019 4 07 2019 19 12 2019 2019 Copyright © 2019 Zhili Xiong et al. This is an open access article distributed under the Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article investigates an adaptive multi-switching synchronization for two identical high-order memristor-based hyperchaotic systems with uncertain parameters. Firstly, the dynamic characteristics of two high-order memristor hyperchaotic systems with uncertain parameters are analyzed. Then, an adaptive multi-switching controller is designed to realize the multi-switching synchronization of the two high-order hyperchaotic systems, and the unknown parameters of the systems are identified to their true values. Furthermore, numerical simulation results testify the effectiveness of the proposed strategy. Finally, the proposed algorithm applied in secure communication of masking encryption and image encryption is validated by statistical analysis. National Natural Science Foundation of China 61673190 F03010 basic research and operation of MOE CCNU18TS042