National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21472056, 21602070]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU15ZX002, CCNU16A05002]
机构署名：
本校为第一且通讯机构
院系归属：
化学学院
摘要：
An I2-promoted formal [3+2] cycloaddition for access to oxazoles has been demonstrated. This is the first example of a Lewis acid-promoted formal [3+2] cycloaddition of isocyanides with methyl ketones involving the C≡N cleavage of isocyanides. The salient feature of this approach is unconventional 2,5-disubstituted oxazole formation from isocyanides and ketones rather than 4,5-substitu...
