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Cyanine-based fluorescent indicator for mercury ion and bioimaging application in living cells

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成果类型:
期刊论文
作者:
Li, Guangjin;Guan, Yihan;Ye, Fengying;Liu, Sheng Hua;Yin, Jun*
通讯作者:
Yin, Jun
作者机构:
[Liu, Sheng Hua; Guan, Yihan; Yin, Jun; Ye, Fengying; Li, Guangjin] Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol, Key Lab Pesticide & Chem Biol,Minist Educ,Hubei I, Wuhan 430079, Peoples R China.
通讯机构:
[Yin, Jun] C
Cent China Normal Univ, Coll Chem, Int Joint Res Ctr Intelligent Biosensing Technol, Key Lab Pesticide & Chem Biol,Minist Educ,Hubei I, Wuhan 430079, Peoples R China.
语种:
英文
关键词:
Cell image;Cyanine;Fluorescent probe;Mercury ion;Near-infrared emission
期刊:
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
ISSN:
1386-1425
年:
2020
卷:
239
页码:
118465
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21676113, 21772054]; Distinguished Young Scholar of Hubei Province [2018CFA079]; 111 ProjectMinistry of Education, China - 111 Project [B17019]; Scholar support program of CCNU [0900-31101090002]; excellent doctorial dissertation cultivation grant of CCNU from the colleges' basic research and operation of MOE [2019YBZZ029]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
A commercial cyanine dye IR-780 and a thioether-containing dicarboxylic acid ligand were used to construct the near-infrared fluorescent probe, which was used as a near-infrared fluorescent indicator for the determination of mercury ions in water and in living cells. This indicator displayed high specificity towards Hg(2+) without any interference from other detecting species. Especially, the emission at 790nm dramatically increased more than 25 times after interacting with Hg(2+). The binding experiment showed that the indicator formed 1:1 complex with Hg(2+). More, this indicator could be ap...

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