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Nitrobenzoxadiazole Ether-Based Near-Infrared Fluorescent Probe with Unexpected High Selectivity for H2S Imaging in Living Cells and Mice.

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成果类型:
期刊论文
作者:
Gong, Shengyi;Zhou, Enbo;Hong, Jiaxin;Feng, Guoqiang*
通讯作者:
Feng, Guoqiang
作者机构:
[Feng, Guoqiang; Hong, Jiaxin; Gong, Shengyi; Zhou, Enbo] CCNU, Coll Chem, Chem Biol Ctr, Minist Educ,Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
通讯机构:
[Feng, Guoqiang] C
CCNU, Coll Chem, Chem Biol Ctr, Minist Educ,Key Lab Pesticide & Chem Biol, 152 Luoyu Rd, Wuhan 430079, Hubei, Peoples R China.
语种:
英文
期刊:
Analytical Chemistry
ISSN:
0003-2700
年:
2019
卷:
91
期:
20
页码:
13136-13142
基金类别:
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21672080, 21472066]; Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [CCNU19TS007]
机构署名:
本校为第一且通讯机构
院系归属:
化学学院
摘要:
H2S is an important endogenous gasotransmitter, and its detection in living systems is of great significance. Especially, selective and sensitive near-infrared (NIR) fluorescent H2S probes with rapid response and large Stokes shift are highly desirable because of their superiority for in vivo detection. Probes with nitrobenzoxadiazole (NBD) ether as reaction sites have been well-explored recently to detect biothiols or H2S/biothiols simultaneously, rather than to detect H2S selectively. In this work, a new NBD ether-based NIR fluorescent probe ...

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