期刊论文

Zhu, Chengzhou;Li, He;Lin, Yuehe

英文

Analytical Chemistry

0003-2700

2019

91

13

8461-8465

10.1021/acs.analchem.9b01527

C.Z. gratefully acknowledges the financial support by the self-determined research funds of CCNU from the college’s basic research and operation of MOE (CCNU18JCXK07), Fundamental Research Funds for the Central Universities (CCNU19QN066), the Program of Introducing Talents of Discipline to Universities of China (111 program, B17019), and the Recruitment Program of Global Youth Experts of China. H.L. acknowledges financial support from the One-Thousand-Talents Scheme in Sichuan Province.

本校为第一且通讯机构

Improvement in the sensitivity and portability of enzyme-linked immunosorbent assay (ELISA) still faced huge challenges recently. Inspired by the nanoprecipitation process for the carrier-free nanodrug in drug delivery systems, we developed an self-assembly strategy to prepare a kind of all-inclusive allochroic 3,3′,5,5′-tetramethylbenzidine (TMB) nanoparticles for developing improved ELISA (named TLISA). During the self-assembly of TMB molecules, the antibody as signal recognition units and bovine serum albumin as the stabilizing agents coul...