期刊论文

Gong, Jingming

英文

Analytical Chemistry

0003-2700

2020

92

16

11476-11483

10.1021/acs.analchem.0c02839

This work was supported by National Science Foundation of China (Grant 21777052), National Key R&D Program of China (Grant 2018YFC1802003), the Project for Application Foundation Frontier for Wuhan (Grant 2019020701011486), Self-determined Research Funds of CCNU from the Colleges’ Basic Research and Operation of MOE (CCNU18TS013), and The Program of Introducing Talents of Discipline to Universities of China (111 program, B17019).

本校为第一且通讯机构

Antibiotic resistance, encoded via particular genes, has become a major global health threat and substantial burden on healthcare. Hence, the facile, low-cost, and precise detection of antibiotic resistance genes (ARGs) is crucial in the realm of human health and safety, especially multiplex sensing assays. Here, a smart pH-regulated switchable photoelectrochemical (PEC) bioassay has been created for ultrasensitive detection of two typical subtypes of penicillin resistance genes bla-CTX-M-1 (target 1, labeled as TDNA1) and bla-TEM (target 2, la...