National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [22077044, 21672080]
机构署名：
本校为第一且通讯机构
院系归属：
化学学院
摘要：
As a CO donor, CORM-3 is widely used nowadays to study the role of CO as a gasotransmitter and potential drug in biological systems. Developing methods to detect CORM-3 in live systems will contribute to these studies. Herein, we developed a novel Pd2+-free near-infrared fluorescent probe CORM3-AE for detecting CORM-3 both in live cells and in vivo. We found that the allyl ether group in CORM3-AE could be cleaved by CORM-3 directly via an isomerization process to release the NIR fluorophore QCy7 and cause distinct NIR fluorescence changes. Impo...
