期刊论文

中文

生物工程学报

1000-3061

2023

39

07

2730-2742

国家自然科学基金(31401762,31672355) 国家重点研发计划(2017YFD0200400) 武汉市青年科技晨光计划项目(2017050304010320) 遗传调控与整合生物学湖北省重点实验室课题(GRIB202210)。

本校为第一机构

细胞致瘤基因(cellular-myelocytomatosis viral oncogene,c-Myc)编码的c-Myc蛋白通过Wnt/β-catenin信号通路调节相关基因的表达,近年来引起了广泛的研究关注。本研究...展开更多 细胞致瘤基因(cellular-myelocytomatosis viral oncogene,c-Myc)编码的c-Myc蛋白通过Wnt/β-catenin信号通路调节相关基因的表达,近年来引起了广泛的研究关注。本研究旨在利用原核表达系统体外表达棉铃虫(Helicoverpa armigera)c-Myc(Ha-c-Myc)基因,制备多克隆抗体,明确Ha-c-Myc的时空表达模式,并探究Ha-c-Myc在调控棉铃虫胆固醇载体蛋白-2(sterol carrier protein-2,SCP-2)基因表达中的潜在作用。通过PCR扩增Ha-c-...

c-Myc protein encoded by c-Myc(cellular-myelocytomatosis viral oncogene)gene regulates the related gene expression through the Wnt/β-catenin signaling pathway,and has received extensive attention in recent years.The purpose of this study was to express Helicoverpa armig...MORE c-Myc protein encoded by c-Myc(cellular-myelocytomatosis viral oncogene)gene regulates the related gene expression through the Wnt/β-catenin signaling pathway,and has received extensive attention in recent years.The purpose of this study was to express Helicoverpa armig...