Experimental investigation on the factors affecting VWF damage based on an in vitro blood-shearing platform Response to reviewers:

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成果类型：

期刊论文

作者：

Xu Mei*;Lian Hou;Yu-Lin Chen;Hao Mei;Ying-Ying Zhong

通讯作者：

Xu Mei

作者机构：

[Lian Hou] School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.

State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

College of Humanities and tourism, Jianghai Polytechnic College, Yangzhou 225101, China.

[Ying-Ying Zhong] College of Education, Central China Normal University, Wuhan 430079, China.

[Xu Mei] School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.<&wdkj&>State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

通讯机构：

[Xu Mei] S

School of Mechanical and Electrical Engineering, Silicon Lake Vocational and Technical College, Suzhou 215006, China.<&wdkj&>State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China.

语种：

英文

关键词：

VWF damage;shear stress;exposure time;hemolysis;blood-shearing platform

期刊：

Biomedical Engineering Communications

年：

2023

卷：

期：

页码：

DOI：

10.53388/BEMC2023021

机构署名：

本校为其他机构

院系归属：

教育学院

摘要：

With the increasing number of people suffering from heart failure, ventricular assist devices have gradually become an effective way to treat end-stage heart failure. However, the blood damage caused by ventricular assist devices has not been effectively solved, which is an obstacle to its clinical promotion. Most research focused on erythrocyte damage under shear stress, while few researches were conducted on the interaction between blood under shear stress and the induction of von Willebrand factor(VWF) damage. This research used a vortex oscillator blood-shearing platform to conduct in vitr...

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Experimental investigation on the factors affecting VWF damage based on an in vitro blood-shearing platform Response to reviewers:

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