A novel hybrid bifunctional sensing platform for simultaneous determination of NO and 02 has been developed, whereby hematite nanotubes are immobilized into the chitosan matrix onto a gold electrode (labeled as HeNTs-Chi/Au). The HeNTs distributed in porous-structured chitosan matrix not only offer abundant active sites for bifunctional sensing of NO and 02, but also facilitate oxidation of NO and reduction of 02 dramatically. Straight calibration curves are achieved in analyte concentration ranges of 5.0 x 10(-8) to 1.25 x 10(-6) mol L-1 for NO and 2.5 x 10(-7) to 6.0 x 10(-6) mol L-1 for O-2...