Purpose: Numerous studies have confirmed that formaldehyde is genotoxic and mutagenic to mammalian cells. It can induce a broad spectrum of genetic effects. In order to investigate the direct effect of formaldehyde on the proliferation of cells, we undertook this study. Approach: The L-02 and hepatoma SSMC 7721 cell lines were exposed to various concentrations of formaldehyde in vitro. MTT assay was used to evaluate the effects of formaldehyde on the proliferation. Finding: The results showed that the cells' proliferation was enhanced after being treated with low dosages of formaldehyde. Howev...
